Results 71 to 80 of about 124,483 (300)

Expanding Our Boundaries With Information Literacy

, 2002
Years ago I had a calling to a special ministry, but I didn\u27t think of it that way. At the time it seemed more a desire, whereas callings had to do with going into overseas missionary work or into a full time Christian ministry.
Breivik, Patricia Senn
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Economic Development of Rural Areas in Border Territories: Threats and Opportunities

Agriculture
Given the focus of this publication, most of the works included are case studies that address different issues related to the development of border areas: energy transition, food sufficiency, tourism development, social capital, the balance between ...
Francisco Javier Castellano-Álvarez, Paulo Ferreira, Luís Loures, Rafael Robina-Ramírez   +3 more
doaj   +1 more source

ImageSieve: Exploratory search of museum archives with named entity-based faceted browsing [PDF]

, 2010
Over the last few years, faceted search emerged as an attractive alternative to the traditional "text box" search and has become one of the standard ways of interaction on many e-commerce sites.
Cove, Hearst, Hoeber, Marchionini, Olsen, Perugini   +5 more
core   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Analysis of cubic permutation polynomials for turbo codes

, 2012
Quadratic permutation polynomials (QPPs) have been widely studied and used as interleavers in turbo codes. However, less attention has been given to cubic permutation polynomials (CPPs).
D. Tărniceriu, Daniela Tarniceriu, G. H. Hardy, H. Zhao, H. Zhao, J. G. Proakis, J. Ryu, J. Sun, J. Yuan, Lucian Trifina, R. Garello, S. Benedetto, Y. O. Takeshita, Y. O. Takeshita, Y.-L. Chen   +14 more
core   +1 more source

Borsa Parole – A Market for Linguistic Speculation [PDF]

, 2012
This article describes a novel approach to linguistic field research consisting in exploiting the self-regulation of a market for collecting data on language use.
Bry, François, Kneißl, Fabian
core   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Transmedia Practices and Collaborative Strategies in Informal Learning of Adolescents

Social Sciences, 2020
Transmedia literacy is the evolution from traditional media literacy to informal learning and participatory cultures. It analyzes the media literacy processes of young people through communities of practice in participatory contexts and through the use ...
Javier Gil Quintana, Sara Osuna-Acedo
doaj   +1 more source