Results 91 to 100 of about 27,515,164 (308)

TRIZ for Digital Systems Engineering: New Characteristics and Principles Redefined

Systems, 2019
While innovation from the systems engineer is desirable at every step in all phases of systems engineering, there must be a methodology to evaluate alternatives.
Kari Lippert, Robert Cloutier
doaj   +1 more source

How Digital Systems Are Used in Swedish Home Care Nursing Practice: A Qualitative Interview Study to Identify Challenges and Opportunities. [PDF]

Comput Inform Nurs, 2023
Persson J, Larsson R, Erlingsdottir G, Rydenfält C.   +3 more
europepmc   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

The impact of electronic pathways and digital systems on neck of femur fracture outcomes globally: a systematic review. [PDF]

Ann R Coll Surg Engl, 2023
Tandon D, Curlewis K, Vusirikala A, Subramanian P, Patel A.   +4 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Research on Automatic Measurement Method of Three-dimensional Gamma Dose Rate Radiation Field Based on VSLAM

Yuanzineng kexue jishu
To address the need for rapid acquisition of gamma radiation field information in nuclear facility sites and digital radiation protection systems, simultaneous localization and mapping (SLAM) technology was combined with gamma dose detection technology ...
LI Hui1, 2, 3, ,  FAN Qing1,  LI Hua1, 2, 3, ,  LIU Liye1, 2, 3,  CHEN Faguo1, 2, 3,  LI Deyuan1,  ZHAO Yuan1, 2, 3
doaj   +1 more source

Transitioning to Digital Systems: The Role of World Health Organization's Digital Adaptation Kits in Operationalizing Recommendations and Interoperability Standards. [PDF]

Glob Health Sci Pract, 2022
Tamrat T, Ratanaprayul N, Barreix M, Tunçalp Ö, Lowrance D, Thompson J, Rosenblum L, Kidula N, Chahar R, Gaffield ME, Festin M, Kiarie J, Taliesin B, Leitner C, Wong S, Wi T, Kipruto H, Adegboyega A, Muneene D, Say L, Mehl G.   +20 more
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Scoping review exploring the impact of digital systems on processes and outcomes in the care management of acute kidney injury and progress towards establishing learning healthcare systems. [PDF]

BMJ Health Care Inform, 2021
Chew CKT, Hogan H, Jani Y.
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source