Results 81 to 90 of about 27,515,164 (308)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Fundamentals of Digital Image Processing

Control of Color Imaging Systems, 2018
Introduction. 1. Two Dimensional Systems and Mathematical Preliminaries. 2. Image Perception. 3. Image Sampling and Quantization. 4. Image Transforms. 5. Image Representation by Stochastic Models. 6. Image Enhancement. 7. Image Filtering and Restoration.
Anil K. Jain
semanticscholar   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Using assurance frameworks to manage the risks and uncertainties of an energy sector digital spine

IET Smart Grid
The energy transition requires a profound transformation of the entire energy system. The adoption of diverse, distributed renewable energy sources into the energy mix requires many assets, actions, stakeholders, and decisions to communicate with each ...
Henry James Thraves, Anna Theoharis, Wai Yan Sonia Pang, Graham Faiz, Matthew Celnik   +4 more
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

The Fourth Age of Political Communication: Democratic decay or the rise of phronetic political communication?

Nordicum-Mediterraneum, 2016
The ‘fourth age’ of political communication is emerging. In the fourth age the logics of media and digitization shapes the public sphere, because algorithms and polarized drama increasingly determine what we become aware of in digital and mass media. The
Peter Aagaard
doaj  

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Do Digital Systems and Concepts in Modern Public Service Production Have a Negative Impact on Citizens as End-users?

Nordicum-Mediterraneum, 2016
Do digital systems and concepts in modern public service production have a negative impact on citizens as end-users? To answer this research question, we shall first present our theoretical framework ‘the institutional logics perspective’ and show how we
John Storm Pedersen, Jacob Dahl Rendtorff   +1 more
doaj  

Graphene-infused terracotta acoustic sound amplifiers

Scientific Reports
This work introduces a novel approach for enhancing mobile audio performance by incorporating graphene-infused terracotta as an acoustic amplifier. Leveraging the high thermal conductivity and mechanical strength of graphene, this study demonstrates the ...
T. R. Rajalekshmi, Shilpa Pavithran, Rinku Rani Das, Alex James   +3 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source