Results 141 to 150 of about 3,509,576 (320)

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Generative discovery of partial differential equations by learning from math handbooks

Nature Communications
Data-driven discovery of partial differential equations (PDEs) is a promising approach for uncovering the underlying laws governing complex systems.
Hao Xu, Yuntian Chen, Rui Cao, Tianning Tang, Mengge Du, Jian Li, Adrian H. Callaghan, Dongxiao Zhang   +7 more
doaj   +1 more source

Digital twin and its applications in the construction industry: A state-of-art systematic review [version 3; peer review: 1 approved, 5 approved with reservations]

Digital Twin
The construction industry has a great impact on social and economic development because of its wide coverage and a large number of stakeholders involved. It is precisely owing to its large volume that technological innovation of the construction industry
Ray Y. Zhong, Shuaiming Su, Yishuo Jiang
doaj   +1 more source

AI-Driven Digital Twin Model for Reliable Lithium-Ion Battery Discharge Capacity Predictions

International Journal of Intelligent Systems
The present study proposes a novel method for predicting the discharge capabilities of lithium-ion (Li-ion) batteries using a digital twin model in practice.
Pranav Nair, V. Vakharia, Milind Shah, Y. Kumar, Marcin Woźniak, Jana Shafi, Muhammad Fazal Ijaz   +6 more
semanticscholar   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Polyanion-stabilized amorphous halide electrolytes with low lithium content for all-solid-state lithium batteries

Nature Communications
Lithium halide solid electrolytes have garnered significant attention owing to their high ionic conductivity and positive electrode compatibility.
Wen Tang, Feilong Wang, Shuaika Liang, Fiaz Hussain, Jo-chi Tseng, Pengcheng Yu, Jiuwei Lei, Hailun Jin, Chunlei Zhao, Haochang Zhang, Zhepu Shi, Ying Li, Wen Yin, Fucheng Ren, Shuo Wang, Zi‑Feng Ma, Xueliang Sun, Wei Xia   +17 more
doaj   +1 more source

A Digital Twin Framework for Nuclear Power Equipment Maintenance: Design, Prototyping, and Preliminary Validation [version 2; peer review: 3 approved, 3 approved with reservations]

Digital Twin
Throughout the lifecycle of Nuclear Power Equipment (NPE), maintaining high-safety maintenance services is essential for optimal operation. Traditional time-based maintenance strategies are limited in NPE contexts due to stringent safety requirements and
Qingfeng Xu, Qian Huang, Fengtian Chang, Yifan Zhi, Min Zhang, Guanghui Zhou, Chao Zhang   +6 more
doaj   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Application of digital twin for industrial process control: A case study of gauge-looper-tension optimized control in strip hot rolling [version 2; peer review: 2 approved]

Digital Twin
During the hot rolling process, the performance of most control systems gradually degrades due to equipment aging and changing process conditions. However, existing gauge-looper-tension control method remain restricted by a lack of intelligent parameter ...
Shang Chen, Jie Sun, Wen Peng, Cheng-yan Ding, Dian-hua Zhang   +4 more
doaj   +1 more source

An agricultural digital twin for mandarins demonstrates the potential for individualized agriculture

Nature Communications
A digital twin is a digital representation that closely resembles or replicates a real world object by combining interdisciplinary knowledge and advanced technologies. Digital twins have been applied to various fields, including to the agricultural field.
Steven Kim, Seong Heo
semanticscholar   +1 more source