Results 131 to 140 of about 3,378,227 (313)

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Is it possible to develop a digital twin for noise monitoring in manufacturing? [version 2; peer review: 1 approved, 3 approved with reservations, 1 not approved]

Digital Twin
Noise monitoring is important in the context of manufacturing because it can help maintain a safe and healthy workspace for employees. Current approaches for noise monitoring in manufacturing are based on acoustic sensors, whose measured sound pressure ...
Moritz Glatt, Jan Mertes, Jan C. Aurich, Li Yi, Ali Karnoub, Patrick Ruediger-Flore   +5 more
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

The use of Digital Twin for predictive maintenance [PDF]

openQuesto elaborato si concentra sulla manutenzione degli impianti industriali e in particolar modo sulla manutenzione predittiva. Al giorno d'oggi per la manutenzione viene utilizzato il Digital Twin.
DALL'IGNA, CHIARA
core  

Digital twins for conservation - Digital twin strategy

, 2023
The digital documentation process that was addressed for the knowledge, conservation and management of Pier Luigi Nervi’s Turin Exhibition Center reflected the complexity of the object and required an immense effort to develop a novel, holistic approach, tailored to the strong, interdisciplinary nature of the research.
Giacomo Patrucco, Stefano Perri, Giulia Sammartano, Antonia Spano'   +3 more
openaire   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Hybrid Spatial–Sequence Modeling for Joint Fish Species and Disease Classification in Marine Aquaculture

Journal of Marine Science and Engineering
Fish disease and species identification is critical for intelligent aquaculture, directly influencing productivity, sustainability, and economic viability.
Zeeshan Ahmad, Jiacheng Xia, Armindo H. Cambule, Shudi Bao, Zhengjie Ji, Hao Zheng, Meng Chen   +6 more
doaj   +1 more source

Digital twins for metrology; metrology for digital twins

Measurement Science and Technology
Abstract Digital twinning is a rapidly growing area of research. Digital twins combine models and data to provide up-to-date information about the state of a system. They support reliable decision-making in fields such as structural monitoring and advanced manufacturing.
Louise Wright, Stuart Davidson
openaire   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source