Results 51 to 60 of about 97,141 (337)
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
The digital simulation of a turbo-charged diesel engine [PDF]
, 1969 A mathematical simulation of a six cylinder four stroke water cooled diesel engine is described and then used to study the changes in performance caused by variations of engine paramters and operating conditions.
Hodgetts, D., Shroff, H. D.
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji +13 more
wiley +1 more source
Defining a Digital Twin: A Data Science-Based Unification
Machine Learning and Knowledge Extraction, 2023 The concept of a digital twin (DT) has gained significant attention in academia and industry because of its perceived potential to address critical global challenges, such as climate change, healthcare, and economic crises.
Frank Emmert-Streib
doaj +1 more source
Heterodyne Holography with full control of both signal and reference arms
, 2015 Heterodyne holography is a variant of phase shifting holography in which reference and signal arms are controlled by acousto optic modulators. In this review paper, we will briefy describe the method and its properties, and we will illustrate its ...
Gross, Michel
core +3 more sources
Digital Twin (DT) based methodology to support effective design of industrial production lines
Procedia Computer Science, 2023 The paper proposes a digital twin (DT) based methodology to support effective design of industrial production lines. In particular the authors define the design guidelines of an industrial production line by using an approach based on multiple performance measures, Design of Experiments (DOE) and multiple performance measures.
Cimino, Antonio +3 more
openaire +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source
Optimal control theory based design of elasto-magnetic metamaterial [PDF]
, 2017 A method to design a new type of metamaterial is presented. A two-step strategy to define an optimal long-range force distribution embedded in an elastic support to control wave propagation is considered. The first step uses a linear quadratic regulator
Carcaterra, A. +4 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective Somatic items used in depression assessments can potentially overlap with symptoms related to physical illness, including systemic sclerosis (SSc). No studies have looked at whether somatic depression items may be influenced by diffuse versus limited SSc disease subtypes, which are associated with varying degrees of symptom presentation.
Sophie Hu +110 more
wiley +1 more source