Results 131 to 140 of about 37,303,817 (298)

Iterative calibration of medical digital twins via adaptive estimators

Frontiers in Applied Mathematics and Statistics
While iterative calibration of computational models is a fundamental aspect of digital twins, it has been largely overlooked. Instead of focusing on parameter identification for static models, the implementation of digital twins requires not only high ...
Juan E. Sereno, Havilah Neujahr, Miguel Hernandez-Gonzalez, Esteban A. Hernandez-Vargas   +3 more
doaj   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Unlocking the Potential of Digital Twins in Construction: A Systematic and Quantitative Review Using Text Mining

Buildings
The construction industry has been trying to enhance the level of digitalization and autonomy by adopting various communication and information technologies (ICT), e.g., augmented reality (AR), virtual reality (VR), robotics, drones, or building ...
Jisoo Park, Jae-Kang Lee, Min-Jae Son, Chaeyeon Yu, Jaesung Lee, Sungjin Kim   +5 more
doaj   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

Introduction to digital twins for smart metabolic circular cities: Foundations, technologies, practices, and emerging trends

This introductory chapter sets the stage for the edited book titled, “Digital Twins for Smart Metabolic Circular Cities: Innovations in Urban Planning and Climate Resilience.” It establishes the foundation for this work by exploring the critical role of ...
Yigitcanlar, Tan, Huang, Jeffrey, Bibri, Simon Elias   +2 more
core   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Data-Driven Hierarchical Digital Twins of Social Interactions

Social interactions are inherently complex, shaped by dynamic trust building, biases, and adaptive strategies. Yet in laboratory settings, their study is often constrained by small datasets that nonetheless encode rich and sophisticated cognitive ...
Peter Kirsch, Stefanie Lis, Georgia Koppe, Stephanie N.L. Schmidt, Daniel Durstewitz, Ismail Guennouni, Manuel Brenner   +6 more
core   +1 more source

Digital twin for Industrial Internet

Fundamental Research
Industrial Internet upgrades the traditional industrial manufacturing to digitization, networking and intellectualization era, which calls for brand-new technology supports. As a promising solution, the emergence Digital Twin (DT) offers enhanced digital mapping capability with strong feasibility, security, economic and intelligence, which fits well ...
Li, Yushuai, Zhang, Yan
openaire   +4 more sources

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif, Diane Demailly, Gabriella A. Horvàth, Juan Dario Ortigoza Escobar, Nathalie Dorison, Mayté Castro Jiménez, Cécile A. Hubsch, Thomas Wirth, Gun‐Marie Hariz, Sophie Huby, Morgan Dornadic, Zohra Souei, Muhammad Mushhood Ur Rehman, Simone Hemm, Mehdi Boulaymen, Eduardo M. Moraud, Jocelyne Bloch, Xavier Vasques   +17 more
wiley   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source