Results 111 to 120 of about 5,201,214 (300)

The work of the digital undead: digital capitalism and the suspension of communicative death [PDF]

Continuum, 2019
In den vergangenen Jahren erregten Online-Dienste wie LivesOn, Eterni.me und DeadSocial einige Aufmerksamkeit in den Medien. Solche Services scheinen die Hoffnung zu wecken, den Tod mithilfe digitaler Mittel zu suspendieren, da sie einige kommunikative Aspekte der verstorbenen Person aufrechterhalten.
openaire   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Information seeking in the Humanities: physicality and digitality [PDF]

, 2008
This paper presents a brief overview of a research project that is examining the information seeking practices of humanities scholars. The results of this project are being used to develop digital resources to better support these work activities ...
Blandford, A., Buchanan, G., Gow, J., Rimmer, J., Warwick, C.   +4 more
core  

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Perceived income stability and financial security among gig workers in Indonesia: a socioeconomic and occupational analysis

Business: Theory and Practice
The gig economy of flexible, platform-mediated, and task-based work has been reshaping the labour markets of countries worldwide, including Indonesia. Gig workers usually operate without formal contracts or social protection and face unique challenges ...
Nurmala Ahmar, Andri Setia Dharma, Dwi Prastowo Darminto   +2 more
doaj   +1 more source

Studying Law Students’ Information Seeking Behaviour to Inform the Design of Digital Law Libraries [PDF]

, 2006
In this paper, we describe our ongoing work which involves examining the information seeking behaviour of legal professionals. This work involves studying the behaviour of both academic and practicing lawyers with the long-term aim of integrating ...
Blandford, A., Cox, A.L., Makri, S.
core  

Working on Digital Platforms

Journal of Medical & Clinical Nursing, 2021
This study aims to discuss work on digital platforms. Therefore, it addresses labor relations in the information society; explains the “new” figures that emerged with parasubordination; and it explains what is conventionally called uberization, emphasizing the uncertainty and instability to which workers are exposed.
openaire   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source