Results 1 to 10 of about 59,145 (338)
Divergent Electrophysiologic Effects of Sacubitril in Digitalis- and Pinacidil-Related Shortened Repolarization: Experimental Evidence for Harmful Effects of Digitalis Glycosides [PDF]
PharmaceuticsBackground: Recent studies reported an abbreviation of cardiac repolarization induced by sacubitril. Thus, the purpose of this study was to evaluate the electrophysiologic effects of sacubitril in the presence of drugs that shorten the QT interval ...
Christian Ellermann +7 more
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Clinical Impact of Digitalis Therapy in a Large Multicenter Cohort of CRT-Recipients [PDF]
Journal of Cardiovascular Development and Disease(1) Introduction: Digitalis use in patients with severe heart failure is controversial. We assessed the effects of digitalis therapy on mortality in a large, observational study in recipients of cardiac resynchronization therapy (CRT).
Julia W. Erath +7 more
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Digitalis Therapy Is Associated With an Increased Risk of ICD Shock Delivery and Device Revision [PDF]
Annals of Noninvasive ElectrocardiologyBackground Digitalis glycosides are employed for rate control of atrial fibrillation and treatment of heart failure. Previous studies suggested potential harmful effects of digitalis therapy.
Gerrit Frommeyer +9 more
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Endogenous Digitalis-like Factors: An Overview of the History
Frontiers in Endocrinology, 2015 The sodium pump is a ubiquitous cell surface enzyme, a Na, K ATPase, which maintains ion gradients between cells and the extracellular fluid (ECF). The extracellular domain of this enzyme contains a highly conserved binding site, a receptor for a plant ...
Vardaman eBuckalew
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THE EFFECT OF DIGITALIS ON THE NORMAL HUMAN ELECTROCARDIOGRAM, WITH ESPECIAL REFERENCE TO A-V CONDUCTION [PDF]
Journal of Experimental Medicine, 1916 Digitalis was given by mouth to five normal young male adults in amounts ranging from 2.0 to 3.0 gm. of standardized leaves in the course of 7 to 10 days.
Paul D. White, Robert Ray Sattler
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Utilizing Big Data to Identify Tiny Toxic Components: Digitalis
Foods, 2021 The botanical genus Digitalis is equal parts colorful, toxic, and medicinal, and its bioactive compounds have a long history of therapeutic use. However, with an extremely narrow therapeutic range, even trace amounts of Digitalis can cause adverse ...
Elizabeth Sage Hunter +2 more
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Anais Brasileiros de Dermatologia, 2012 Infantile digital fibromatosis or Reye's tumor is a benign fibroproliferative tumor, the etiopathogenesis of which has yet to be fully clarified. It typically presents at birth or in the first year of life and is characterized by a firm, flesh colored or
Luciane Francisca Fernandes Botelho +5 more
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Destructive effect of digitalis overdose on blood-brain barrier in rats; an experimental study [PDF]
Journal of Research in Clinical Medicine, 2020 Introduction: Cardiac glycosides are widely used in critical cardiac diseases despite their unexplained mechanisms on cardio-respiratory system and other autonomic complications within both intra-uterine and post-natal life.
Mehmet Nuri Kocak +5 more
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Al-Kitab Journal for Pure Sciences, 2023 This study was undertaken to compare the electrolytes K, and Na levels serum of (67) toxic digitalis uremic heart failure patients and their levels in the serum of 50 digitalis (not toxic) heart failure patients. The electrolyte level of K and Na was
Firdaws A. AL-Mashhadani
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