Results 261 to 270 of about 66,597 (341)

The Missing Link in Digital Transformation Leadership: Unpacking the Role of Knowledge

Information Systems Journal, EarlyView.
ABSTRACT Leading digital transformation (DT) is challenging due to the unforeseen hurdles that arise through the novelty of digital technologies and the broad scope of organisational change. Even those with a wealth of experience and skills may struggle to respond adequately to inherently novel situations.
Malmi Amadoru, Wietske Van Osch, Luc Gosselin   +2 more
wiley   +1 more source

"Cardiac glycosides"-quo vaditis?-past, present, and future? [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Fender J, Klöcker J, Boivin-Jahns V, Ravens U, Jahns R, Lorenz K.   +5 more
europepmc   +1 more source

Deprescribing Benzodiazepine Receptor Agonists in Older Adults and People With Cognitive Impairment: A Systematic Review

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Benzodiazepine receptor agonists (BZRAs) (benzodiazepines and z‐drugs) may provide limited benefits in the management of insomnia when used short‐term. However, they increase the risk of harms including falls, fractures, hospitalizations, and cognitive impairment. Deprescribing (cessation) of BZRAs may be beneficial for older adults
Aisling M. McEvoy, Aili V. Langford, Shin J. Liau, Darshna Goordeen, Emily Reeve, Justin P. Turner   +5 more
wiley   +1 more source

Mendelian randomization analysis reveals the potential of the IKZF1 gene as a therapeutic target in colorectal cancer. [PDF]

Discov Oncol
Lin J, Xu Q, Zhao Z.
europepmc   +1 more source

Digitalis intoxication [PDF]

Postgraduate Medical Journal, 1972
openaire   +2 more sources

Respiratory Syncytial Virus (RSV)‐Related Hospitalization and Increased Rate of Cardiovascular Events in Older Adults

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Recent studies suggest that respiratory syncytial virus (RSV) can cause severe illness in terms of in‐hospital outcomes and mortality. The degree to which RSV hospitalization is associated with cardiovascular outcomes, particularly those known to occur following acute respiratory infections, is poorly described. Methods We conducted
Chris P. Verschoor, Joshua O. Cerasuolo, Joseph M. Caswell, Mark Tatangelo, Atilio Costa‐Vitali, David W. Savage, Jeffrey C. Kwong   +6 more
wiley   +1 more source

Addressing the Evolution of Cardenolide Formation in Iridoid-Synthesizing Plants: Site-Directed Mutagenesis of PRISEs (Progesterone-5β-Reductase/Iridoid Synthase-like Enzymes) of Plantago Species. [PDF]

Molecules
Dorfner M, Klein J, Senkleiter K, Lanig H, Kreis W, Munkert J.   +5 more
europepmc   +1 more source

Almost billfish: convergent longirostry, micro‐dentition, and possible glandular sinuses in a large teleost fish from the Upper Cretaceous of Northern Italy

Journal of Anatomy, EarlyView.
A fossil rostrum fragment of a large teleost fish from the Upper Cretaceous of Northern Italy reveals remarkable anatomical convergences with Cenozoic and Recent billfishes (marlins, swordfishes, and akin). The extinct group Plethodidae independently acquired a long snout, micro‐teeth, and oil‐gland sinuses well before the evolution of true billfishes.
Giovanni Serafini, Jürgen Kriwet, Tommaso Toldo, Eliana Fornaciari, Jacopo Amalfitano, Giorgio Carnevale   +5 more
wiley   +1 more source

Incorporating Network Pharmacology and Experimental Validation to Identify Bioactive Compounds and Potential Mechanisms of Digitalis in Treating Anaplastic Thyroid Cancer. [PDF]

ACS Omega
Zhu L, Liang R, Guo Y, Cai Y, Song F, Hu Y, Liu Y, Ge M, Zheng G.   +8 more
europepmc   +1 more source