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The use of digitalis glycosides in sinus rhythm. [PDF]
Clinical Science, 1978 Historical perspective Throughout the last 200 years the use of digitalis glycosides has constantly revealed the weakness of the contemporary understanding of congestive heart failure; in consequence the reputation of these drugs has either soared or slumped according to physicians’ prejudices.
A. Guz, D. Mchaffie
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On the Differences Between Ouabain and Digitalis Glycosides
American Journal of Therapeutics, 2014Digoxin and digitoxin are widely used in the treatment of heart diseases. The exact mechanism of action of these drugs has remained an enigma. Ouabain has become the standard tool to investigate the mode of action of cardiotonic steroids, and results with ouabain are regarded as generally valid for all cardiac glycosides.
H. Fuerstenwerth
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The Clinical Pharmacology of Digitalis Glycosides: A Review
The American Journal of The Medical Sciences, 1968AbstractThe metabolic half-times and excretion rates of labeled cardiac glycosides are related to pharmacologic or therapeutic activity. Digoxin, a short-acting glycoside, is excreted primarily in the urine and has a serum half-time of 34 hours.
Doherty Je
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Detection of Digitalis Glycosides on Paper Chromatograms
Nature, 1952Neher and Wettstein1 have used a solution of antimony trichloride in organic solvent to identify certain steroids on paper chromatograms. Although Jaminet2 has used an acetic anhydride solution of antimony trichloride for the spectrophotometric identification of cardiac glycosides, he has not reported its use with paper chromatograms.
D. Lawday
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Clinical pharmacology of digitalis glycosides.
Annual Review of Medicine, 1975J. Doherty, J. Kane
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Immunomodulatory properties of antihypertensive drugs and digitalis glycosides
Expert Review of Cardiovascular Therapy, 2022Introduction The role of chronic inflammatory process in the pathogenesis or exacerbation of hypertension has been already acknowledged. Areas covered Therefore, one can speculate that hypotensive drugs may exert some of their therapeutic effects due to ...
Paweł Bryniarski +2 more
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Clinical pharmacokinetics of digitalis glycosides.
Progress in Cardiovascular Diseases, 1978J. Doherty +4 more
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Digitalis Glycosides: Pharmacokinetics and Their Clinical Implications
Annals of Internal Medicine, 1973J. Doherty
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Acta Clinica Belgica, 2020
We report a case of a 19-year-old woman who ingested Digitalis purpurea leaves as a suicide attempt. She developed gastro-intestinal symptoms, loss of colour vision, cardiac conduction disturbances as well as an elevated serum potassium.
K. Maes +5 more
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We report a case of a 19-year-old woman who ingested Digitalis purpurea leaves as a suicide attempt. She developed gastro-intestinal symptoms, loss of colour vision, cardiac conduction disturbances as well as an elevated serum potassium.
K. Maes +5 more
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Clinical value of the radioimmunoassay of the digitalis glycosides.
Pharmacological Reviews, 1973T. Smith, E. Haber
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