Results 91 to 100 of about 32,919 (306)
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Mapping the digitalisation of European political parties
An increasing number of comparative case studies explore the drivers and impacts of digital technologies on political parties (Bennet et al., 2018.
Sandri, Giulia +6 more
core +1 more source
The cloud technologies for mathematics teachers training
This article is devoted to modern approaches to interpretations of "the cloud technology", the types of cloud computing application for teachers training are discussed. A comparative analysis of Web-SCM SAGE and The Sagemath Cloud is made.
M. V. Popel
doaj +1 more source
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Service models of the cloud-based learning environment of the educational institution
The article is devoted to creating and development of the cloud based educational and scientific environment of higher education institutions, using modern approaches to the ICT infrastructure design, based on the different types of service models ...
Mariya P. Shyshkina
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
MIDE - Multidisciplinary Institute of Digitalisation and Energy 2008-2013
Aalto-yliopiston MIDEtutkimusohjelma keskittyi pitkäjänteiseen perustutkimukseen digitalisoitumisen ja energiakysymysten aloilla. Ohjelman tavoitteena oli huipputason osaamisen luominen, opetuksen vahvistaminen ja suomalaisen elinkeinoelämän ...
core
Digitalisation toolkit for SMEs
The digitalisation toolkit combines technological and methodological competencies tailored for small and medium-sized enterprises. In a series of workshops, participants learn the fundamentals of process optimisation and digitalisation through a learning
Gering, Patrick
core
Development of human monoclonal antibodies against TARM1 by yeast display
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
How can we understand the disruptive forces of digitalisation?
Elaluf-Calderwood, Silvia +3 more
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