Results 121 to 130 of about 119,540 (319)
Digidem Digest - Issue 30 (October 2020) [PDF]
The Digidem Digest literature radar was a monthly curated overview of the latest publications with relevance to the research group "Democracy and Digitalization" at the Weizenbaum Institute.
Thiel, Thorsten
core +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Digital, digitized, and numerical humanities
Abstract The term ‘digital humanities’ may be understood in three different ways: as ‘digitized humanities’, by dealing essentially with the constitution, management, and processing of digitized archives; as ‘numerical humanities’, by putting the emphasis on mathematical abstraction and the development of numerical and formal models ...
openaire +2 more sources
Digital humanities, digital methods, digital history, and digital outputs: History writing and the digital revolution [PDF]
Abstract While the term “digital humanities” appears inclusive, its exact meaning remains unclear and its early association with studies in English Literature means the term has already been partially superceded by “digital methods.” However, that renaming is problematic as it emphasises the research tools used while the field itself ...
openaire +2 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Digidem Digest - Issue 10 (January 2019) [PDF]
The Digidem Digest literature radar was a monthly curated overview of the latest publications with relevance to the research group "Democracy and Digitalization" at the Weizenbaum Institute.
Thiel, Thorsten
core +1 more source
Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Hydrostatic piezoelectric properties of 1-3 type piezo-composite with a porous polymer matrix
Piezoelectric sensors for underwater sonar require high hydrostatic piezoelectric properties (dh, gh and HFOM), and research is being conducted on various types of piezoelectric composites to improve them. In this study, research was conducted to improve
Jong-Ho Kim +4 more
doaj +1 more source
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source

