Results 111 to 120 of about 180,573 (319)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Digidem Digest - Issue 29 (August 2020)

open access: yes, 2020
The Digidem Digest literature radar was a monthly curated overview of the latest publications with relevance to the research group "Democracy and Digitalization" at the Weizenbaum Institute.
Thiel, Thorsten
core   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

Digidem Digest - Issue 40 (September 2021)

open access: yes, 2021
The Digidem Digest literature radar was a monthly curated overview of the latest publications with relevance to the research group "Democracy and Digitalization" at the Weizenbaum Institute.
Thiel, Thorsten
core   +1 more source

Hydrostatic piezoelectric properties of 1-3 type piezo-composite with a porous polymer matrix

open access: yesJournal of Asian Ceramic Societies
Piezoelectric sensors for underwater sonar require high hydrostatic piezoelectric properties (dh, gh and HFOM), and research is being conducted on various types of piezoelectric composites to improve them. In this study, research was conducted to improve
Jong-Ho Kim   +4 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Digidem Digest - Issue 38 (July 2021)

open access: yes, 2021
The Digidem Digest literature radar was a monthly curated overview of the latest publications with relevance to the research group "Democracy and Digitalization" at the Weizenbaum Institute.
Thiel, Thorsten
core   +1 more source

Deep learning model for real time moisture content detection and prediction in white tea withering using near infrared spectroscopy

open access: yesScientific Reports
This study proposes a novel deep learning model, named STA-BiGRU-XGBoost, for predicting moisture content during the white tea withering process using near-infrared spectroscopy.
Wei Tao   +7 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

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