Results 91 to 100 of about 119,540 (319)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Digital (In)Equality, Digital Inclusion, Digital Humanism

open access: yes12th ACM Conference on Web Science Companion, 2020
From its inception, the World Wide Web has been intended to be a force for social good. But there are many barriers and obstacles, a situation commonly characterized as the Digital Divide. Several billion people especially in the Global South do not have access to Internet/Web for reasons of lacking (affordable) infrastructure, poverty, low literacy ...
Anna Bon, Hans Akkermans
openaire   +2 more sources

How hand-made affects consumers’ perceived nutritional quality of organic food

open access: yesFrontiers in Nutrition
This study analyzed the impact of handmade in depth on consumers’ perceived nutritional quality of organic food through three experiments. Experiment 1 found that handmade significantly enhanced consumers’ positive perceptions of nutritional quality of ...
Qin Liu   +4 more
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Digitalization of investment-innovative activities of the trade business entities in network IT-system [PDF]

open access: yes, 2021
The problem of digital business transformation through innovative development in the country, which affects the transformation of business structures, including trade, remains underdeveloped, which requires further scientific, methodological, practical ...
Karman, Serhii   +12 more
core  

Digidem Digest - Issue 25 (April 2020) [PDF]

open access: yes, 2020
The Digidem Digest literature radar was a monthly curated overview of the latest publications with relevance to the research group "Democracy and Digitalization" at the Weizenbaum Institute.
Thiel, Thorsten
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Computing Logarithms Digit-by-Digit

open access: yesBRICS Report Series, 2004
In this work, we present an algorithm for computing logarithms of positive real numbers, that bares structural resemblance to the elementary school algorithm of long division. Using this algorithm, we can compute successive digits of a logarithm using a 4-operation pocket calculator.
openaire   +2 more sources

In search of mechanisms for organizing digitalization [PDF]

open access: yes, 2016
The development and maintenance of digital products interacting with large scale infrastructures requires new ways for organizing innovation. Contradictory requirements, conflicting needs and managerial challenges emerge from the interplay between local ...
SPAGNOLETTI, PAOLO
core  

Digitalisering i sykepleietjenesten [PDF]

open access: yes, 2019
Our healthcare system is undergoing considerable transformation; standards are changing and established ways of working are being challenged. One change that has consequences for nursing services is increasing digitalization, with new information systems
Jorun Danielsen, Inger   +14 more
core   +1 more source

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