Results 91 to 100 of about 271,772 (303)

University Libraries are Changing to Encourage More Student Use [PDF]

open access: yes, 2012
Dramatic decrease of users in reference services is a trend observed all around the world. Rather than talking with students face to face at the library, we librarians provide virtual reference with email and instant message. On the other hand, there are
Good, Hiroyuki N
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

How does digitalization affect headquarters and what does it mean for CEE-focused headquarters in Austria? [PDF]

open access: yes, 2019
Headquarters (HQs) represent central units within corporationsi and their goal is to add value to the firm and its respective subunits. They do so by taking over various responsibilities, such as allocating resources within the firm, coordinating and ...
Decreton, Benoit   +2 more
core  

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Hydrostatic piezoelectric properties of 1-3 type piezo-composite with a porous polymer matrix

open access: yesJournal of Asian Ceramic Societies
Piezoelectric sensors for underwater sonar require high hydrostatic piezoelectric properties (dh, gh and HFOM), and research is being conducted on various types of piezoelectric composites to improve them. In this study, research was conducted to improve
Jong-Ho Kim   +4 more
doaj   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

DIGIT - DIGItal sTeps

open access: yes, 2016
Despite the great technological evolution felt in recent decades in the media field towards the automation of audio post-production processes that did not occur in the practise of sound foley, which remains a manual process that is based on the technical and interpretive skills of a foley artist.
openaire   +2 more sources

Piggybacking on an Autonomous Hauler: Business Models Enabling a System-of-Systems Approach to Mapping an Underground Mine

open access: yes, 2017
With ever-increasing productivity targets in mining operations, there is a growing interest in mining automation. In future mines, remote-controlled and autonomous haulers will operate underground guided by LiDAR sensors.
Borg, Markus   +2 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

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