Results 71 to 80 of about 180,573 (319)

Digidem Digest - Issue 32 (December 2020)

open access: yes, 2020
The Digidem Digest literature radar was a monthly curated overview of the latest publications with relevance to the research group "Democracy and Digitalization" at the Weizenbaum Institute.
Thiel, Thorsten
core   +1 more source

Digital humanities and digital social reading [PDF]

open access: yesDigital Scholarship in the Humanities, 2019
Abstract Prominent among the social developments that the web 2.0 has facilitated is digital social reading (DSR): on many platforms there are functionalities for creating book reviews, ‘inline’ commenting on book texts, online story writing (often in the form of fanfiction), informal book discussions, book vlogs, and more.
Simone Rebora   +10 more
openaire   +5 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Digidem Digest - Issue 5 (August 2018)

open access: yes, 2018
The Digidem Digest literature radar was a monthly curated overview of the latest publications with relevance to the research group "Democracy and Digitalization" at the Weizenbaum Institute.
Thiel, Thorsten
core   +1 more source

Generalized Design Methodology for Dual-Arm Robotic Platforms: From Conceptualization to Experimental Validation Within the MANiBOT Framework

open access: yesMachines
This work proposes a general methodology for the design and experimental validation of dual-arm robotic platforms intended for intelligent manipulation tasks in real-world environments.
Mario Peñacoba-Yagüe   +1 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Toward deep assessments: On the possibility of decolonial digital technologies

open access: yesTATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis
Considering the coloniality of current digital tools and their increasingly massive global social and ecological impacts, we explore the question of what socio-cultural assemblages can contribute to deep civilizational transformations.
Dorian Cavé, Rainer Rehak
doaj   +1 more source

Integrated planning of grids and energy conversion units in municipal multi-energy carrier systems

open access: yesEnergy Informatics, 2021
The ongoing energy transition requires the planning of low-emission municipal energy supply systems. These systems comprise distribution grids for electricity, gas, and heat, as well as energy conversion units such as heating systems. This paper presents
Christopher Hauk   +2 more
doaj   +1 more source

Digital Collections and Digital Collecting Practices [PDF]

open access: yesProceedings of the 33rd Annual ACM Conference on Human Factors in Computing Systems, 2015
Reference is increasingly made to ‘digital collections’, yet this term encompasses accumulated digital objects of varying form, purpose and value. We review social science literature on mate-rial collections and draw from in-depth interviews with 20 peo-ple in the UK in order to offer a clearer understanding of what constitutes a digital collection and
Rebecca D. Watkins   +2 more
openaire   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

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