Results 61 to 70 of about 118,501 (319)

Digital Reset. Redirecting Technologies for the Deep Sustainability Transformation

open access: yes, 2022
Time seems out of joint. The world society has experienced a centennial pandemic, the global thermometer has displayed a sequence of hottest years on record, and Russia’s war on Ukraine has shattered political order.
Digitalization for Sustainability (D4S)
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Toward deep assessments: On the possibility of decolonial digital technologies

open access: yesTATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis
Considering the coloniality of current digital tools and their increasingly massive global social and ecological impacts, we explore the question of what socio-cultural assemblages can contribute to deep civilizational transformations.
Dorian Cavé, Rainer Rehak
doaj   +1 more source

Digitalization and cost efficiency in the repacking operations of a 3PL part distribution center

open access: yes, 2023
reservedThe purpose of this master’s thesis is to describe the project of digitalization and cost efficiency that was underway in the inbound operations inside the third-party logistics (3PL) warehouse of an electric car manufacture company, located in ...
ZAUSA, ALEX
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Generalized Design Methodology for Dual-Arm Robotic Platforms: From Conceptualization to Experimental Validation Within the MANiBOT Framework

open access: yesMachines
This work proposes a general methodology for the design and experimental validation of dual-arm robotic platforms intended for intelligent manipulation tasks in real-world environments.
Mario Peñacoba-Yagüe   +1 more
doaj   +1 more source

Integrated planning of grids and energy conversion units in municipal multi-energy carrier systems

open access: yesEnergy Informatics, 2021
The ongoing energy transition requires the planning of low-emission municipal energy supply systems. These systems comprise distribution grids for electricity, gas, and heat, as well as energy conversion units such as heating systems. This paper presents
Christopher Hauk   +2 more
doaj   +1 more source

Digital Collections and Digital Collecting Practices [PDF]

open access: yesProceedings of the 33rd Annual ACM Conference on Human Factors in Computing Systems, 2015
Reference is increasingly made to ‘digital collections’, yet this term encompasses accumulated digital objects of varying form, purpose and value. We review social science literature on mate-rial collections and draw from in-depth interviews with 20 peo-ple in the UK in order to offer a clearer understanding of what constitutes a digital collection and
Rebecca D. Watkins   +2 more
openaire   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Phasing the barriers to Industry 4.0: Enhancing the understanding of the challenges of digitalization [PDF]

open access: yes
Although Industry 4.0 has intensified the focus on the digitalization of manufacturing operations, the success stories are still far apart. To develop appropriate roadmaps toward Industry 4.0, it is essential to understand the barriers and inhibiting ...
Buer, Sven-Vegard   +2 more
core   +1 more source

Home - About - Disclaimer - Privacy