Results 61 to 70 of about 271,772 (303)

Integrated planning of grids and energy conversion units in municipal multi-energy carrier systems

open access: yesEnergy Informatics, 2021
The ongoing energy transition requires the planning of low-emission municipal energy supply systems. These systems comprise distribution grids for electricity, gas, and heat, as well as energy conversion units such as heating systems. This paper presents
Christopher Hauk   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Digital lifestyle – digital citizenship – digital pedagogy

open access: yesOpus et Educatio, 2019
„2017 from within the EU the Internet access households ratio has risen to 87%, which is 32% points exceed the ten years ago, 2007 levels. In 2017, 85% of the EU households used broadband network, which is approximately the double of the 2007 ratio.
openaire   +2 more sources

Standardization Framework for Sustainability from Circular Economy 4.0 [PDF]

open access: yes, 2019
The circular economy (CE) is widely known as a way to implement and achieve sustainability, mainly due to its contribution towards the separation of biological and technical nutrients under cyclic industrial metabolism.
Aguayo-González, Francisco   +4 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Trajectory Tracking Nonlinear Hybrid Control of Automated Guided Vehicles

open access: yesComplexity
Automated guided vehicles (AGVs), so necessary in industrial environments, require precise control of trajectory tracking to make accurate stops at logistics stations, such as loading stations, or to pick up or drop off trolleys, pallets, or racks.
Antonio Sánchez-Rodríguez   +3 more
doaj   +1 more source

PURITY: An Industry-Standard-Based Security Framework for IT-OT Convergence

open access: yesIEEE Access
The convergence of Information Technology (IT) and Operational Technology (OT) introduces complex cybersecurity challenges, particularly for industrial control systems.
Franz-Karl Schachinger   +2 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Defining Digitalities I: What’s Digital about Digits?

open access: yes, 2023
Modern discourses emphasizes electronic immateriality as the defining feature of digital technology. The idea that digits might be digital when punched onto cards, or even written on a piece of pa- per, is no longer intuitive. Yet by reconstructing the context in which the categories of digital and analog were first distinguished histori- cally in the ...
openaire   +2 more sources

Social, administrative and educational dimensions of the “human – subject of economic life” phenomenon under conditions of information society transition to a new level of development [PDF]

open access: yes, 2020
Перехід інформаційного суспільства на новий рівень розвитку в тріаді генезисних процесів «становлення – формування – розвиток» спричинює численні зміни.
Голодюк, Л. С.   +1 more
core  

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