Results 61 to 70 of about 203,083,182 (242)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Digitalization in Education Sector

open access: yes, 2018
In today's world, digitalization has been a game changer in one of the most important sectors- Education. It has been effectively used as a prominent technique in the whole gamut of education sector. It has blurred the boundaries of physical distance, as
Dr. Satish Marathe
core   +1 more source

Automation of Production Planning in the Context of Digitalization in the Aspect of Employees Continuing Education [PDF]

open access: yes, 2021
This article is devoted to continuing education and analysis of approaches to the study of the production planning automation process in the context of digitalization.
Natalia, P. (Popova)   +5 more
core   +1 more source

Digital transformation in higher education:a systematic review

open access: yes大数据, 2023
Promoting digital transformation becomes the key to achieving high-quality development of education.Based on the survey of the current situation of education digitalization, the essence, development, and related techniques of education digitalization ...
Haihong QIAN, Maoyi WANG, Yun XIONG
doaj  

PAPER for an Educational Digital Library

open access: yes, 2003
GeogDL is a digital library of geography examination resources designed to assist students in revising for a national geography examination in Singapore. As part of an iterative design process, we carried out participatory design and brainstorming with student and teacher design partners. The first study involved prospective student design partners. In
Dion Hoe-Lian Goh   +3 more
openaire   +4 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Digitalization of teacher education

open access: yesNordic Journal of Comparative and International Education, 2020
This paper examines emerging epistemologies in the wake of increased digitalization and the extent to which student teachers are prepared for such epistemologies in their teacher education (TE) programs.
Andreas Lund, Toril Aagaard
doaj  

Institutional Traps of Digitalization of Russian Higher Education

open access: yesВысшее образование в России, 2021
In 2016-2018 the state in Russia adopted a package of program documents, which implies the transfer of education to the large-scale introduction of digital technologies. This phenomenon has been called “digitalization of education”.
M. A. Golovchin
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Digitalization of medical and healthcare education in a Low- and middle-income country: a mixed-method case study of institutional transformation at Yerevan State Medical University

open access: yesFrontiers in Digital Health
IntroductionDigitalizing healthcare professionals' education for the future is essential to ensure the availability of skilled medical professionals across settings, particularly in low- and middle-income countries (LMICs), including underprivileged and ...
Karine Sargsyan   +11 more
doaj   +1 more source

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