Results 71 to 80 of about 203,083,182 (242)

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Digital Maturity in Education

Nordic Journal of Digital Literacy
As educational institutions navigate the complexities of digital transformation, understanding the factors that drive successful technology integration is essential. The implementation of digital tablets in schools is becoming increasingly common. Through the application of the digital maturity framework, a Structural Equation Modeling (SEM) analysis ...
Nielsen, Bettina, Egeberg, Gunstein Christoffer, Svihus, Cathrine   +2 more
openaire   +2 more sources

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Research commissioned by the Japanese Ministry of Education, Culture, Sports, Science and Technology On the promotion of digitalization of learning materials : A model for the development of procedures for lifelong learning based on the promotion of digitalization of learning materials [PDF]

, 2008
During three years (2004-2006) and commissioned by the Ministry of Education, Culture, Sports, Science and Technology, the author participated as principal researcher in the project "ON THE PROMOTION OF DIGITALIZATION OF LEARNING MATERIALS".
フルイチ, カツヤ, FURUICHI, Katsuya, 684, 685, 古市, 勝也   +4 more
core  

Selling out Education in the Name of Digitalization: A Critical Analysis of Swedish Policy

Nordic Journal of Studies in Educational Policy, 2021
Sweden aspires to become ‘the best in the world at utilizing the opportunities of digitalization’ and is internationally recognized for its digital performance.
Marita Ljungqvist, Anders Sonesson
doaj   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

DIGITALIZATION OF HIGHER EDUCATION – A NEW STAGE OF INFORMATION? [PDF]

, 2020
The article reveals the main differences between the concepts of education informatization and education digitalization. The mechanism of interaction of the subjects of the educational process in terms of informatization and digitalization of education ...
Loginova, S. L., Логинова, С. Л.   +1 more
core   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

Digital Education

DigitCult@Scientific Journal on Digital Cultures
In this chapter the author has proposed a digital shift towards the education system, highlighting the constitutional validity of the same, and backing it up with the pronouncements of Indian judiciary. As the chapter is divided into various parts, international recognition of education and also importance of digital education has been pressed upon ...
Heru Susanto, Fang-Yie Leu, Saad Haj Bakry, A. K. Haghi   +3 more
  +6 more sources

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source