Results 131 to 140 of about 71,019 (306)

The emotional landscape of applied linguistics in digital spaces: Theories, research, and praxis

open access: yesAustralian Journal of Applied Linguistics
In this Editorial, we introduce the Special Issue, emphasizing the need to critically explore how digital learning environments affect language educators’ and learners’ emotional experiences.
Luis Javier Pentón Herrera   +2 more
doaj   +1 more source

The imperial war museum’s social interpretation project [PDF]

open access: yes, 2013
This report represents the output from research undertaken by University of Salford and MTM London as part of the joint Digital R&D Fund for Arts and Culture, operated by Nesta, Arts Council England and the AHRC.
Bagnall, G   +5 more
core  

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

open access: yesAdvanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun   +7 more
wiley   +1 more source

Modified Stage-Gate: A Conceptual Model of Virtual Product Development Process [PDF]

open access: yes, 2009
In today’s dynamic marketplace, manufacturing companies are under strong pressure to introduce new products for long-term survival with their competitors.
Ahmed, Shamsuddin   +2 more
core   +4 more sources

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

open access: yesAdvanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao   +16 more
wiley   +1 more source

“Scoundrel press” vs. Costa Rican executive branch: online conflict press delegitimization, and implications for e-democracy

open access: yesFrontiers in Communication
IntroductionThis article examines the discursive conflict between the Costa Rican executive branch and critical news media during the first two years of Rodrigo Chaves's administration, situating the case within broader debates on political communication
José Pablo Salazar-Aguilar   +1 more
doaj   +1 more source

The new shape of the student

open access: yes, 2012
This chapter critically examines student characteristics in light of the popular dis-course which describes students as part of a net generation of digital native young people. Digital and networked technologies have clearly changed the possibilities for
Jones, Chris
core  

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

open access: yesAdvanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim   +6 more
wiley   +1 more source

Public relations and reputation resilience: an applied study of Facebook’s crisis management strategies

open access: yesFrontiers in Communication
IntroductionThe study investigates the role of public relations strategies in fostering reputation resilience during crises on digital platforms, with a specific focus on Facebook. The research is grounded in Situational Crisis Communication Theory (SCCT)
Omnia Mohamed Ahmed Salem   +5 more
doaj   +1 more source

Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids

open access: yesAdvanced Science, EarlyView.
Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang   +12 more
wiley   +1 more source

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