Results 131 to 140 of about 1,075 (245)

PANX2 Suppresses Lung Adenocarcinoma Progression by Inducing Disulfidptosis and Enhancing Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
ABSTRACT Lung adenocarcinoma (LUAD) remains a leading cause of cancer mortality with limited therapeutic options. Disulfidptosis, a novel cell death modality driven by disulfide stress, represents a promising target, yet its regulation in LUAD is poorly defined. Here, we identify Pannexin 2 (PANX2) as a tumor suppressor in LUAD.
Yi Chen   +7 more
wiley   +1 more source

Virtual Reality and the Sense of Belonging Among Distance Learners: A Study on Peer Relationships in Higher Education

open access: yesVirtual Worlds
Distance learners in higher education are often assumed to face limited peer interaction, potentially weakening their sense of belonging. This study examines peer relationships and belonging among students in distance and blended university programs ...
David Košatka   +4 more
doaj   +1 more source

Tumor‐Infiltrating mregDCs Restrain Anti‐Tumor Immunity in Early Relapse HCC

open access: yesAdvanced Science, EarlyView.
Tumor‐infiltrating mregDCs are regulated by the TNFR2‐non‐canonical NF‐κB axis, which is mediated by TNF‐α secreted by CD161+CD8+ T cells. These mregDCs recruit CD161+CD8+ T cells via the CCL20‐CCR6 axis, forming a positive feedback loop that enhances immunosuppression, promotes early recurrence of HCC, and further confirms TNFR2 as a key therapeutic ...
Zefan Zhang   +13 more
wiley   +1 more source

Pragmatic Language Choices in the Digital Age: A Comparative Study of Tanzanian and Pakistani Undergraduates

open access: yesمجلة العلوم و آفاق المعارف
Digital communication has reshaped how multilingual speakers make pragmatic language choices in everyday interaction. Digital platforms reorganize language through speed, multimodality, and technical affordances in emerging multilingual societies.
Nasir Razzaq   +2 more
doaj   +1 more source

Origami‐Mediated Low‐Voltage Electret Soft Robotic Actuators for Human‐Machine Haptic Interfaces

open access: yesAdvanced Science, EarlyView.
This work introduces an origami‐mediated soft electret actuator that combines compliant mechanical design and enhanced charge retention for low‐voltage vibrotactile feedback. The device delivers reliable tactile cues, demonstrates durable performance under continuous actuation, and enables intuitive interaction in applications such as tactile ...
Han Chen   +8 more
wiley   +1 more source

A thematic and bibliometric analysis of trends and future directions in da’wah research

open access: yesCogent Arts & Humanities
This study examines the evolving trends and future directions of da’wah research through an integrated bibliometric–thematic analysis, a dual methodological approach rarely applied in Islamic communication studies.
Muhammad Munif   +8 more
doaj   +1 more source

Supramolecular Assembly of Stepped‐Persistent ROS Nanogenerator for Sustained Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
ROS catalytic systems often fail to achieve both effective tumor elimination and persistent immune activation due to their monotonous ROS production profiles. A stepped‐persistent ROS nanogenerator was developed by supramolecularly assembling multiple ROS generation modules within a nanofiber structure to simultaneously extend ROS generation duration ...
Zhenqiang Wang   +10 more
wiley   +1 more source

Digital religion in platform societies: authority, mediation, and social cohesion in algorithmic publics (2010–2025)

open access: yesFrontiers in Sociology
This article critically synthesizes scholarship on digital religion and social cohesion published between 2010 and 2025. Drawing on a corpus of eighty-eight studies, we show that contemporary religious communication is increasingly governed by platform ...
Ismaael AlMazaedh   +5 more
doaj   +1 more source

Mastication‐Induced Electrical Stimulation Activates Prg4+ Chondroprogenitors for Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
This study presents a ″trash‐to‐treasure″ strategy that converts harmful joint overloads into beneficial electrical cues. The biodegradable MagPie, by providing piezoelectrical stimulation and releasing Mg2+ during mastication, exerts synergistic pro‐regenerative and anti‐inflammatory effects on Prg4+ cells via the ECM‐mediated FAK‐PI3K‐Akt axis ...
Shi‐Yang Feng   +10 more
wiley   +1 more source

Hypermedia in the Ambient Wood [PDF]

open access: yes, 2003
The Ambient Wood project, carried out as part of the Equator IRC, set out to provide an augmented learning experience for children in an outdoor environment.
Mark J. Weal   +7 more
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