Results 321 to 330 of about 76,806 (392)

Opportunities and obstacles of electronic health records in Italy: towards enhanced surgical care. [PDF]

Acta Otorhinolaryngol Ital
Corbisiero MF, Rizzo D, Gallus R, Loreti P, Bracciale L, Bussu F.   +5 more
europepmc   +1 more source

Digitised Armorials

, 2014
openaire   +2 more sources

Inhibition of OATP1B1/3 Rather Than UGT1A1 May Be the Major Cause of the Bilirubin Elevation After Atazanavir Administration

Clinical Pharmacology &Therapeutics, EarlyView.
Atazanavir has been reported to increase total serum bilirubin level up to ninefold. It is widely believed that the observed total bilirubin elevation is primarily due to UGT1A1 inhibition. However, UGT enzymes are well‐known as a low‐affinity and high‐capacity system, and the observed drug–drug interaction mediated by UGTs is usually less than twofold.
Jin Dong, Pradeep Sharma, Rasha Emara, Derek Cheung, Weifeng Tang, Diansong Zhou, David W. Boulton, Mats Någård, Miki S. Park   +8 more
wiley   +1 more source

Data for whom? Experiences and perceptions of a perinatal eRegistry in two hospitals in Mtwara region, Tanzania. [PDF]

BMJ Glob Health
Molenaar J, Kikula A, Kionga Y, Berenge HT, Benova L, van Olmen J, Hanson C, Abeid M, Pembe AB.   +8 more
europepmc   +1 more source

Digitisation and technological challenges of the banking industry

, 2019
Panagiotis Roumeliotis
openalex   +2 more sources

Model‐Informed Selection of the Recommended Phase 2 Dosage for Anti‐TIGIT Immunotherapy Leveraging co‐Expressed PD‐1 Inhibitor Target Engagement

Clinical Pharmacology &Therapeutics, EarlyView.
Refining dose projections requires a deep understanding of drug‐target relationships at the site of action, which is often challenging to achieve. Here we present a case study of how one can refine dose projections for a TIGIT‐targeted immunotherapy by leveraging information from the well‐studied PD‐1 pathway since the co‐expression of PD‐1 and TIGIT ...
Irina Kareva, Ping Hu, Vadryn Pierre, Thomas Kitzing, Anja Victor, Emilia Richter, Wei Gao, Karthik Venkatakrishnan, Anup Zutshi   +8 more
wiley   +1 more source

Joint treatment of geometry and radiance for 3D model digitisation

, 2014
Kenneth Vanhoey
openalex   +1 more source

Education and Democracy in the Time of Digitisation

, 2019
Mike Douse, Philip Uys
openalex   +2 more sources

A Comprehensive CYP2D6 Drug–Drug–Gene Interaction Network for Application in Precision Dosing and Drug Development

Clinical Pharmacology &Therapeutics, EarlyView.
Conducting clinical studies on drug–drug‐gene interactions (DDGIs) and extrapolating the findings into clinical dose recommendations is challenging due to the high complexity of these interactions. Here, physiologically‐based pharmacokinetic (PBPK) modeling networks present a new avenue for exploring such complex scenarios, potentially informing ...
Simeon Rüdesheim, Helena Leonie Hanae Loer, Denise Feick, Fatima Zahra Marok, Laura Maria Fuhr, Dominik Selzer, Donato Teutonico, Annika R. P. Schneider, Juri Solodenko, Sebastian Frechen, Maaike van der Lee, Dirk Jan A. R. Moes, Jesse J. Swen, Matthias Schwab, Thorsten Lehr   +14 more
wiley   +1 more source