Results 101 to 110 of about 337,861 (317)

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

open access: yesAdvanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng   +8 more
wiley   +1 more source

Digitization initiatives: a reconnaissance of the global landscape

open access: yes, 2008
Digitization has become quite a buzzword around libraries and library organizations. Conferences, symposia and workshops on digitization are becoming more popular and many general conferences feature a technology or digitization track.
Swanepoel, Marinus
core  

Digitizing the Historical Periodical Collection at the Al-Aqsa Mosque Library in East Jerusalem [PDF]

open access: yes, 2009
The Arab Press in Palestine developed at the turn of the twentieth century and proliferated for several decades despite restrictions imposed under the Ottoman Empire and during the British Mandate Period (1917-1948).
Abu Harb, Qasem, Matusiak, Krystyna
core  

Nigra‐Subthalamic Dopaminergic Circuitry Modulates and Represents Distinct Pain Modality in Physiological and Pain States in Mice

open access: yesAdvanced Science, EarlyView.
Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji   +13 more
wiley   +1 more source

Digitization, Cataloging & Metadata Mailing (February 2014)

open access: yes, 2014
Table of contents includes: RDA Notes; (Un-)Controlling Undifferentiated Personal Name Headings; "RDA Basics" Webinars for Early 2014; Digital Preservation Resource Highlight; Call for Presenters for MDL 12th Annual Meeting; Note From the EditorMinitex ...
Minitex Digitization, Cataloging & Metadata Education Unit
core  

An Overview of Digitization of Information Resources [PDF]

open access: yes, 2009
This paper highlights basic steps and mechanisms involved in creating and documenting an electronic text or similar digital resources emphasizing the tools, techniques, standards that are adopted in the process of creation of e-resources with intent to ...
Panda, K. C., Swain, Dillip K.
core  

3D Large‐Scale Subwavelength‐Resolution Sound Sheet Tomography Based on an Active and Programmable Circular Meta‐Array

open access: yesAdvanced Science, EarlyView.
A programmable 2048‐element circular ultrasound array combined with a compact acoustic lens produces a thin “sound sheet” over a large field of view, and records echoes with wide angular diversity across the ring aperture. Coherence‐enhanced beamforming converts full‐matrix data into high‐contrast tomographic slices, delivering near‐diffraction‐limited
Qiu‐De Zhang   +11 more
wiley   +1 more source

Variable Rate Seeding and Accuracy of Within-Field Hybrid Switching in Maize (Zea mays L.)

open access: yesAgronomy
Precision agriculture techniques, such as variable rate seeding (VRS) and hybrid switching, play an important role in optimizing crop yield and reducing input costs.
Károly Bűdi   +3 more
doaj   +1 more source

Digitization, Cataloging & Metadata Mailing (April/May 2015)

open access: yes, 2015
Table of contents includes: DCME Welcomes Elizabeth Baus; ARLD Day Summary; Texas Conference on Digital Libraries; MDL Annual Meeting Registration Open; New Contributions to Minnesota Reflections; Conference and Event Highlights; Minnesota's Contribution
Minitex Digitization, Cataloging & Metadata Education Unit
core  

THE DIGITIZATION OF IFE HEADS: MUSEUMS AND THE CHALLENGES OF REPATRIATION OF AFRICAN ARTEFACTS

open access: yes, 2022
reservedABSTRACT For the decade of years, the meanings and interpretation of artifacts that were taken from African culture including the Ife bronze heads have been produced and fixed by a team of western curatorial experts (Ciolfi, 2012).
OYAWOLE, FOLUKE MARY
core  

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