Results 121 to 130 of about 325,809 (336)

Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors

open access: yesAdvanced Science, EarlyView.
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon   +10 more
wiley   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang   +18 more
wiley   +1 more source

Foundation Model‐Enabled Multimodal Deep Learning for Prognostic Prediction in Colorectal Cancer with Incomplete Modalities: A Multi‐Institutional Retrospective Study

open access: yesAdvanced Science, EarlyView.
FLARE, a multimodal AI framework, combines pathology slides, radiology scans, and clinical reports to predict colorectal cancer outcomes, even when some tests are missing. Evaluated retrospectively in 1679 patients from four medical centers, it consistently achieved the best prognostic accuracy and clearly separated high‐ and low‐risk groups.
Linhao Qu   +6 more
wiley   +1 more source

Proposal for an IMLS Collection Registry and Metadata Repository [PDF]

open access: yes, 2002
The University of Illinois at Urbana-Champaign proposes to design, implement, and research a collection-level registry and item-level metadata repository service that will aggregate information about digital collections and items of digital content ...
Bennett, Nuala A.   +4 more
core  

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

open access: yesAdvanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu   +11 more
wiley   +1 more source

Drivers of Forest Structural Complexity in Mountain Forests of Nepal

open access: yesMountain Research and Development
Forests in the Himalayan region are crucial for maintaining the region's ecological balance, conserving biodiversity, and supporting the livelihoods of local people.
Prakash Basnet   +4 more
doaj   +1 more source

Publications and Observational Data in the Archive of Konkoly Observatory [PDF]

open access: yes, 2007
We present the status of ongoing digital preservation projects at Konkoly Observatory. The electronic IBVS, the Communications/Mitteilungen series and observational data digitization are discussed, with some open ...
Holl, András
core  

The SST Fully-Synchronous Multi-GHz Analog Waveform Recorder with Nyquist-Rate Bandwidth and Flexible Trigger Capabilities

open access: yes, 2014
The design and performance of a fully-synchronous multi-GHz analog transient waveform recorder I.C. ("SST") with fast and flexible trigger capabilities is presented.
Chiem, Edwin   +2 more
core   +2 more sources

An Ultrathin, Cyano‐Functionalized Copolymeric Memristor by iCVD Process for Driving Convolutional Neural Networks of High‐Resolution Images

open access: yesAdvanced Science, EarlyView.
Two‐terminal polymer memristors based on cyano‐functionalized copolymer films are developed via a solvent‐free, initiated chemical vapor deposition (iCVD) process for high‐resolution image classification. Molecularly engineered p(CEA‐co‐DEGDVE) films enable stable, linear, and symmetric conductance modulation, supporting multi‐level weight mapping in ...
Ji In Kim   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy