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Nephron, 2017 In a recent issue of Nephron, Abu-Amer et al.[<xref ref-type="bibr" rid="ref1">1</xref>] reported the presence of hypermagnesuria in patients following acute intravenous administration of digoxin and suggested that the Na<sup>+</sup>/K<sup>+</sup>-ATPase γ-subunit, which is the pharmacological target of digoxin, can ...
Zanoli, Luca +2 more
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Progress in Cardiovascular Diseases, 2002
After 200 years of use, digitalis still appears to have a place in our armamentarium for heart failure and atrial fibrillation despite the proven survival benefits with ACE inhibitors and beta-blockers. Digoxin therapy is inexpensive and well tolerated and may result in considerable savings.
Eric J, Eichhorn, Mihai, Gheorghiade
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After 200 years of use, digitalis still appears to have a place in our armamentarium for heart failure and atrial fibrillation despite the proven survival benefits with ACE inhibitors and beta-blockers. Digoxin therapy is inexpensive and well tolerated and may result in considerable savings.
Eric J, Eichhorn, Mihai, Gheorghiade
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Anti‐Digoxin Antibody in Digoxin Intoxication
Australian and New Zealand Journal of Medicine, 1981Abstract: This study was conducted to investigate the action of anti‐digoxin antibody in digoxin intoxication. Anti‐digoxin antibody was raised in sheep and administered to six dogs following intravenous infusion of digoxin (0.04 or 0.16mg/kg body weight), either as whole serum or as partially purified gamma globulin. Plasma and urine digoxin levels,
D, Anderson, R, Penny, M F, O'Rourke
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New England Journal of Medicine, 1971
A variable or poor response to a therapeutic agent may not have its origin in the patient; it may be due to a formulation defect in the drug product administered. The most commonly recognized formulation defect in a dosage form such as a tablet is a deficiency or excess of the active ingredient.
T G, Vitti, D, Banes, T E, Byers
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A variable or poor response to a therapeutic agent may not have its origin in the patient; it may be due to a formulation defect in the drug product administered. The most commonly recognized formulation defect in a dosage form such as a tablet is a deficiency or excess of the active ingredient.
T G, Vitti, D, Banes, T E, Byers
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Clinical Pharmacology and Therapeutics, 1984
Serum digoxin and metabolites were assayed in plasma and urine by HPLC in 10 dialysis-dependent patients with end-stage renal failure (group I) and in five patients with comparatively normal renal function (group II) after ingestion of 150 muCi 3H-digoxin-12 alpha.
M H, Gault +6 more
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Serum digoxin and metabolites were assayed in plasma and urine by HPLC in 10 dialysis-dependent patients with end-stage renal failure (group I) and in five patients with comparatively normal renal function (group II) after ingestion of 150 muCi 3H-digoxin-12 alpha.
M H, Gault +6 more
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Clinical Pharmacology & Therapeutics, 1977
A patient with chronic atrial fibrillation developed hyperthyroidism. Increasing doses of digoxin were required to maintain satisfactory ventricular rate control. The systemic availability of oral digoxin was decreased in this patient. The metabolism of digoxin was studied in hyperthyroid rats.
D H, Huffman +2 more
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A patient with chronic atrial fibrillation developed hyperthyroidism. Increasing doses of digoxin were required to maintain satisfactory ventricular rate control. The systemic availability of oral digoxin was decreased in this patient. The metabolism of digoxin was studied in hyperthyroid rats.
D H, Huffman +2 more
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The American Journal of Cardiology, 1985
Many investigators have studied the potential interactions between calcium-channel antagonists and digoxin. Digoxin is usually well absorbed, and its excretion is dependent on renal mechanisms, primarily glomerular filtration. Several studies have reported a decrease in digoxin clearance and an increase of approximately 50% in digoxin levels when ...
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Many investigators have studied the potential interactions between calcium-channel antagonists and digoxin. Digoxin is usually well absorbed, and its excretion is dependent on renal mechanisms, primarily glomerular filtration. Several studies have reported a decrease in digoxin clearance and an increase of approximately 50% in digoxin levels when ...
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Diseases of the Chest, 1969
1969;56;56-60 Dis Chest Roger W. Jelliffe Administration of Digoxin http://chestjournal.chestpubs.org/content/56/1/56 can be found online on the World Wide Web at: The online version of this article, along with updated information and services ) ISSN:0096-0217 http://chestjournal.chestpubs.org/site/misc/reprints.xhtml ( without the prior written ...
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1969;56;56-60 Dis Chest Roger W. Jelliffe Administration of Digoxin http://chestjournal.chestpubs.org/content/56/1/56 can be found online on the World Wide Web at: The online version of this article, along with updated information and services ) ISSN:0096-0217 http://chestjournal.chestpubs.org/site/misc/reprints.xhtml ( without the prior written ...
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[3H]Digoxin in the Optic Tract in Digoxin Intoxication
Journal of Cardiovascular Pharmacology, 1980Normal and chronically hypokalemic dogs were infused with [3H]digoxin until ventricular tachycardia occurred, at which point the concentration of digoxin was measured in all tissues involved in vision. The highest concentration was found in the choroid-retina of the eye, and this was considered the most likely site for the various visual changes seen ...
P F, Binnion, G, Frazer
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