Results 301 to 310 of about 92,853 (340)

Digoxin in hyperthyroidism [PDF]

open access: possibleClinical Pharmacology & Therapeutics, 1977
A patient with chronic atrial fibrillation developed hyperthyroidism. Increasing doses of digoxin were required to maintain satisfactory ventricular rate control. The systemic availability of oral digoxin was decreased in this patient. The metabolism of digoxin was studied in hyperthyroid rats.
C. D. Klaassen   +2 more
openaire   +2 more sources

A novel source of the cardiac glycoside digoxin from the endophytic fungus Epicoccum nigrum: isolation, characterization, production enhancement by gamma irradiation mutagenesis and anticancer activity evaluation

Journal of Applied Microbiology, 2019
Different endophytic fungi were isolated and screened for their digoxin‐producing ability. Strain improvement and different culture conditions were studied for more effective production of digoxin.
El-Sayed R. El-Sayed   +2 more
semanticscholar   +1 more source

Bioavailability of Digoxin

New England Journal of Medicine, 1971
A variable or poor response to a therapeutic agent may not have its origin in the patient; it may be due to a formulation defect in the drug product administered. The most commonly recognized formulation defect in a dosage form such as a tablet is a deficiency or excess of the active ingredient.
Trieste G. Vitti   +2 more
openaire   +3 more sources

Digoxin and nifedipine

The American Journal of Cardiology, 1985
Many investigators have studied the potential interactions between calcium-channel antagonists and digoxin. Digoxin is usually well absorbed, and its excretion is dependent on renal mechanisms, primarily glomerular filtration. Several studies have reported a decrease in digoxin clearance and an increase of approximately 50% in digoxin levels when ...
openaire   +3 more sources

Digoxin biotransformation

Clinical Pharmacology and Therapeutics, 1984
Serum digoxin and metabolites were assayed in plasma and urine by HPLC in 10 dialysis-dependent patients with end-stage renal failure (group I) and in five patients with comparatively normal renal function (group II) after ingestion of 150 muCi 3H-digoxin-12 alpha.
M H, Gault   +6 more
openaire   +2 more sources

Dissimilarities of Digoxin

New England Journal of Medicine, 1971
Every physician struggles to come up with the "proper digitalizing dose" at some point in his career. At times, it is to survive an internship interview; on other occasions, someone else's future is at stake. In the article by Lindenbaum et al. in the current issue of the Journal, there is information to suggest that the brand of digoxin employed may ...
openaire   +3 more sources

Comparative pharmacodynamics of betamethyl digoxin and digoxin in man

Clinical Pharmacology & Therapeutics, 1977
The positive inotropic effects and serum glycoside levels following intravenous and oral administration of betamethyl digoxin (BMD) were measured and compared with those of digoxin in normal adults. The cardiac inotropy was assessed noninvasively in the abbreviation of the electromechanical systolic index (QS2l) obtained by serial measurements of ...
Gopal Das   +2 more
openaire   +3 more sources

Administration of Digoxin

Diseases of the Chest, 1969
1969;56;56-60 Dis Chest Roger W. Jelliffe Administration of Digoxin http://chestjournal.chestpubs.org/content/56/1/56 can be found online on the World Wide Web at: The online version of this article, along with updated information and services ) ISSN:0096-0217 http://chestjournal.chestpubs.org/site/misc/reprints.xhtml ( without the prior written ...
openaire   +3 more sources

[3H]Digoxin in the Optic Tract in Digoxin Intoxication

Journal of Cardiovascular Pharmacology, 1980
Normal and chronically hypokalemic dogs were infused with [3H]digoxin until ventricular tachycardia occurred, at which point the concentration of digoxin was measured in all tissues involved in vision. The highest concentration was found in the choroid-retina of the eye, and this was considered the most likely site for the various visual changes seen ...
Glenn Frazer, Peter F. Binnion
openaire   +3 more sources

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