Results 31 to 40 of about 5,507 (191)

Hemicrania continua: a report of ten new cases [PDF]

open access: yesArquivos de Neuro-Psiquiatria, 2002
Hemicrania continua (HC) is an uncommon primary headache first described as a syndrome in 1984. Being quite unusual, its clinical characterization still demands better description.
Marcelo E. Bigal   +3 more
doaj   +1 more source

Efficacy of Symptomatic Treatment of Migraine

open access: yesPediatric Neurology Briefs, 2005
The evidence from randomized and clinical controlled trials concerning efficacy and tolerability of symptomatic treatment of migraine in children was reviewed by search of databases from inception to June 2004 at Erasmus Medical Centre, Rotterdam, and ...
J Gordon Millichap
doaj   +1 more source

Polypharmacology guided drug repositioning approach for SARS-CoV2.

open access: yesPLoS ONE, 2023
Drug repurposing has emerged as an important strategy and it has a great potential in identifying therapeutic applications for COVID-19. An extensive virtual screening of 4193 FDA approved drugs has been carried out against 24 proteins of SARS-CoV2 (NSP1-
Esther Jamir   +5 more
doaj   +1 more source

Identification of Anti-HIV/Migraine Drugs as Potential Inhibitors of SARS-Cov2 Main Protease Using in Silico Assessments

open access: yesThe Journal of Qazvin University of Medical Sciences, 2022
Background The acute respiratory syndrome named “COVID-19” is caused by a novel coronavirus called Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
Hanifeh Shariatifar   +3 more
doaj   +1 more source

Ischemic Colitis Secondary to Ergotamine Use: A Case Study

open access: yesCase Reports in Gastroenterology, 2011
A 48-year-old woman with a history of chronic migraines, initially admitted for inpatient management of intractable migraine headaches, developed new onset abdominal pain, hypotension, and diarrhea on hospital day number ten.
Regina E. Rodman   +3 more
doaj   +1 more source

Cerebral Venous Thrombosis with Migraine-Like Headache and the Trigeminovascular System

open access: yesCase Reports in Neurological Medicine, 2016
Cerebral venous thrombosis- (CVT-) associated headache is considered a secondary headache, commonly presenting as intracranial hypertension headache in association with seizures and/or neurological signs. However, it can occasionally mimic migraine.
Fábio A. Nascimento   +3 more
doaj   +1 more source

The role of α1- and α2-adrenoceptor subtypes in the vasopressor responses induced by dihydroergotamine in ritanserin-pretreated pithed rats

open access: yesThe Journal of Headache and Pain, 2017
Background Dihydroergotamine (DHE) is an acute antimigraine agent that displays affinity for dopamine D2-like receptors, serotonin 5-HT1/2 receptors and α1/α2-adrenoceptors. Since activation of vascular α1/α2-adrenoceptors results in systemic vasopressor
Eduardo Rivera-Mancilla   +6 more
doaj   +1 more source

Screening of potential inhibitors targeting the main protease structure of SARS-CoV-2 via molecular docking

open access: yesFrontiers in Pharmacology, 2022
The novel coronavirus disease (COVID-19) caused by SARS-CoV-2 virus spreads rapidly to become a global pandemic. Researchers have been working to develop specific drugs to treat COVID-19.
Xinbo Yang   +3 more
doaj   +1 more source

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo   +11 more
wiley   +1 more source

A Review of Nanoparticle‐Based Astrocyte Modulation in CNS Disorders: Evaluating the Underexplored Potential of Intranasal Delivery

open access: yesNano Select, Volume 7, Issue 1, January 2026.
Nanoparticle‐driven nose‐to‐brain drug delivery offers a noninvasive approach to bypass the blood–brain barrier (BBB) and directly modulate reactive astrocytes in CNS disorders. This review highlights biodegradable nanoparticles for astrocyte modulation, enhancing drug bioavailability, sustained release, and neuroinflammation control.
Senamile M. Dlamini   +3 more
wiley   +1 more source

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