Results 141 to 150 of about 736 (160)
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Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2022
4,4-Dimethyl-substituted sterols are bioactive minor sterols of most animal fats and plant oils, but higher shares are present in lanolin (wool grease). Here, the isolation of the 4,4-dimethyl-substituted sterols dihydrolanosterol and lanosterol from lanolin by countercurrent chromatography (CCC) is described.
Walter Vetter +2 more
exaly +3 more sources
4,4-Dimethyl-substituted sterols are bioactive minor sterols of most animal fats and plant oils, but higher shares are present in lanolin (wool grease). Here, the isolation of the 4,4-dimethyl-substituted sterols dihydrolanosterol and lanosterol from lanolin by countercurrent chromatography (CCC) is described.
Walter Vetter +2 more
exaly +3 more sources
Biomedical Mass Spectrometry, 1981
The fatty acyl moiety in lanosterol and dihydrolanosterol esters was determined by measurement of the metastable transition [M--15]+ leads to [M--15-fatty acid]+ which occurs in the first field free region of a double focusing mass spectrometer. The analysis was made by accelerating voltage scanning.
J C Promé
exaly +3 more sources
The fatty acyl moiety in lanosterol and dihydrolanosterol esters was determined by measurement of the metastable transition [M--15]+ leads to [M--15-fatty acid]+ which occurs in the first field free region of a double focusing mass spectrometer. The analysis was made by accelerating voltage scanning.
J C Promé
exaly +3 more sources
The lymphatic absorption of dihydrolanosterol and cholesterol in the rat.
Research communications in molecular pathology and pharmacology, 1999 Dihydrolanosterol (DHL) and its analogs have been studied extensively as cholesterol biosynthesis inhibitors. They inhibit specific steps in cholesterol synthesis by inhibiting lanosterol demethylase and by suppressing HMG-CoA reductase. The present study was designed to estimate the lymphatic absorption of DHL.
S, Satchithanandam +3 more
openaire +2 more sources
Journal of Separation Science, 2019
AbstractLanosterol is a potential drug for cataracts treatment, which can reverse the aggregation of intracrystalline proteins. The low concentration in lanolin calls for high‐performance separation methods. In this study, a counter‐current chromatography dual‐mode elution method was developed for the first time to separate and purify lanosterol from ...
Jimin Zheng, Xueli Cao, Tian Han
exaly +3 more sources
AbstractLanosterol is a potential drug for cataracts treatment, which can reverse the aggregation of intracrystalline proteins. The low concentration in lanolin calls for high‐performance separation methods. In this study, a counter‐current chromatography dual‐mode elution method was developed for the first time to separate and purify lanosterol from ...
Jimin Zheng, Xueli Cao, Tian Han
exaly +3 more sources
ChemInform, 1991 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Z. PARYZEK, J. MARTYNOW
openaire +2 more sources
Biochemical and Biophysical Research Communications, 1991
The purified lanosterol 14a-demethylase (P-45014DM) of S. cerevisiae catalyzed the 14a-demethylation of 24-methylene-24,25-dihydrolanosterol (24-methylenelanost-8-en-3 beta-ol, 24-methylene-DHL), the natural substrate of the demethylase of filamentous fungi, as well as its natural substrate, lanosterol.
Y, Aoyama, Y, Yoshida
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The purified lanosterol 14a-demethylase (P-45014DM) of S. cerevisiae catalyzed the 14a-demethylation of 24-methylene-24,25-dihydrolanosterol (24-methylenelanost-8-en-3 beta-ol, 24-methylene-DHL), the natural substrate of the demethylase of filamentous fungi, as well as its natural substrate, lanosterol.
Y, Aoyama, Y, Yoshida
openaire +2 more sources
Tetracyclic triterpenes. Part 13. A new synthesis of 4β-demethyl-24,25-dihydrolanosterol
J. Chem. Soc., Perkin Trans. 1, 1991The reaction of 3β-hydroxy-3α-acetyl -14α-methyl-4-nor- 5α-cholest-8-ene toluene-p-sulphonylhydrazone 10 under Bamford–Stevens conditions resulted information of 4α,14α-dimethyl-5α-cholest-8-en-3-one (4β-demethyldihydrolanosterol) and a mixture of 3,14α-dimethyl-4-oxo steroids.
Zdzislaw Paryzek, Jacek Martynow
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ChemInform, 2001
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Masuo Morisaki +2 more
openaire +1 more source
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Masuo Morisaki +2 more
openaire +1 more source