Studies on the mammalian pyruvate dehydrogenase complex: pyruvate dehydrogenase kinase binding sites, reductive acetylation reaction and extrinsic control [PDF]
Call number: LD2668 .T4 BICH 1989 L5Master of ScienceBiochemistry and Molecular Biophysics Interdepartmental ...
Li, Lin.
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Three patients with chronic lacticacidemia and deficiency of the pyruvate dehydrogenase complex demonstrated in cultured skin fibroblasts showed abnormalities on Western blotting with anti-pyruvate dehydrogenase complex antiserum which were not located ...
B. Robinson+5 more
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A novel dihydrolipoyl dehydrogenase-binding protein (E3BP) which lacks an amino-terminal lipoyl domain, p45, has been identified in the pyruvate dehydrogenase complex (PDC) of the adult parasitic nematode, Ascaris suum.
M. Klingbeil+6 more
semanticscholar +1 more source
Human skeletal muscle pyruvate dehydrogenase phosphatase activity and expression : the effect of aerobic capacity [PDF]
Activation of pyruvate dehydrogenase (PDH), which converts pyruvate into acetyl-CoA, is accomplished by a pair of specific phosphatases (PDP 1 & 2). A cross-sectional study investigating the effect of aerobic capacity on PDP activity and expression ...
Love, Lorenzo Kenward.
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The Amidase Domain of Lipoamidase Specifically Inactivates Lipoylated Proteins In Vivo [PDF]
BACKGROUND:In the 1950s, Reed and coworkers discovered an enzyme activity in Streptococcus faecalis (Enterococcus faecalis) extracts that inactivated the Escherichia. coli and E. faecalis pyruvate dehydrogenase complexes through cleavage of the lipoamide
AA Herbert+35 more
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Carbon source feeding strategies for recombinant protein expression in Pichia pastoris and Pichia methanolica [PDF]
Pichia pastoris and Pichia methanolica have been used as expression systems for the production of recombinant protein. The main problems of the production are the slow hierarchic consumption of ethanol and acetate which cause toxicity problems due to ...
Barrera-Avellaneda, LA+3 more
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Crystal Structure of Vinorine Synthase, the First Representative of the BAHD Superfamily*
Vinorine synthase is an acetyltransferase that occupies a central role in the biosynthesis of the antiarrhythmic monoterpenoid indole alkaloid ajmaline in the plant Rauvolfia.
Xueyan Ma+4 more
semanticscholar +1 more source
Engineering of escherichia coli 2-oxoglutarate dehydrogenase complex with mechanistic and synthetic goals [PDF]
The Escherichia coli 2-oxoglutarate dehydrogenase complex (OGDHc) compromises multiple copies of three enzymes - 2-oxoglutarate dehydrogenase (E1o), dihydrolipoyl succinyltransferase (E2o), and dihydrolipoyl dehydrogenase (E3).
Chakraborty, Joydeep
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Structural and biophysical characterization of human pyruvate dehydrogenase multi-enzyme complex [PDF]
Pyruvate dehydrogenase multi-enzyme complex (PDHc) is an assembly of multiple copies of four different proteins. Together they carry out the oxidative decarboxylation of pyruvate and generate acetyl-CoA and NADH, which are components of Krebs cycle ...
Prajapati, Sabin
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The architectural complexity of the human PDC core assembly [PDF]
The mammalian pyruvate dehydrogenase complex (PDC) is a key multi-enzyme assembly linking the glycolytic pathway to the TCA cycle via the specific conversion of pyruvate to acetyl CoA and, as such, is responsible for the maintenance of glucose ...
Vijayakrishnan, Swetha
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