Results 51 to 60 of about 1,484 (136)

Studies on the mammalian pyruvate dehydrogenase complex: pyruvate dehydrogenase kinase binding sites, reductive acetylation reaction and extrinsic control [PDF]

open access: yes, 1989
Call number: LD2668 .T4 BICH 1989 L5Master of ScienceBiochemistry and Molecular Biophysics Interdepartmental ...
Li, Lin.
core  

Defects in the E2 lipoyl transacetylase and the X-lipoyl containing component of the pyruvate dehydrogenase complex in patients with lactic acidemia.

open access: yesJournal of Clinical Investigation, 1990
Three patients with chronic lacticacidemia and deficiency of the pyruvate dehydrogenase complex demonstrated in cultured skin fibroblasts showed abnormalities on Western blotting with anti-pyruvate dehydrogenase complex antiserum which were not located ...
B. Robinson   +5 more
semanticscholar   +1 more source

Identification of a Novel Dihydrolipoyl Dehydrogenase-binding Protein in the Pyruvate Dehydrogenase Complex of the Anaerobic Parasitic Nematode, Ascaris suum(*)

open access: yesJournal of Biological Chemistry, 1996
A novel dihydrolipoyl dehydrogenase-binding protein (E3BP) which lacks an amino-terminal lipoyl domain, p45, has been identified in the pyruvate dehydrogenase complex (PDC) of the adult parasitic nematode, Ascaris suum.
M. Klingbeil   +6 more
semanticscholar   +1 more source

Human skeletal muscle pyruvate dehydrogenase phosphatase activity and expression : the effect of aerobic capacity [PDF]

open access: yes, 2009
Activation of pyruvate dehydrogenase (PDH), which converts pyruvate into acetyl-CoA, is accomplished by a pair of specific phosphatases (PDP 1 & 2). A cross-sectional study investigating the effect of aerobic capacity on PDP activity and expression ...
Love, Lorenzo Kenward.
core  

The Amidase Domain of Lipoamidase Specifically Inactivates Lipoylated Proteins In Vivo [PDF]

open access: yes, 2009
BACKGROUND:In the 1950s, Reed and coworkers discovered an enzyme activity in Streptococcus faecalis (Enterococcus faecalis) extracts that inactivated the Escherichia. coli and E. faecalis pyruvate dehydrogenase complexes through cleavage of the lipoamide
AA Herbert   +35 more
core   +3 more sources

Carbon source feeding strategies for recombinant protein expression in Pichia pastoris and Pichia methanolica [PDF]

open access: yes, 2012
Pichia pastoris and Pichia methanolica have been used as expression systems for the production of recombinant protein. The main problems of the production are the slow hierarchic consumption of ethanol and acetate which cause toxicity problems due to ...
Barrera-Avellaneda, LA   +3 more
core   +2 more sources

Crystal Structure of Vinorine Synthase, the First Representative of the BAHD Superfamily*

open access: yesJournal of Biological Chemistry, 2005
Vinorine synthase is an acetyltransferase that occupies a central role in the biosynthesis of the antiarrhythmic monoterpenoid indole alkaloid ajmaline in the plant Rauvolfia.
Xueyan Ma   +4 more
semanticscholar   +1 more source

Engineering of escherichia coli 2-oxoglutarate dehydrogenase complex with mechanistic and synthetic goals [PDF]

open access: yes, 2019
The Escherichia coli 2-oxoglutarate dehydrogenase complex (OGDHc) compromises multiple copies of three enzymes - 2-oxoglutarate dehydrogenase (E1o), dihydrolipoyl succinyltransferase (E2o), and dihydrolipoyl dehydrogenase (E3).
Chakraborty, Joydeep
core   +1 more source

Structural and biophysical characterization of human pyruvate dehydrogenase multi-enzyme complex [PDF]

open access: yes, 2016
Pyruvate dehydrogenase multi-enzyme complex (PDHc) is an assembly of multiple copies of four different proteins. Together they carry out the oxidative decarboxylation of pyruvate and generate acetyl-CoA and NADH, which are components of Krebs cycle ...
Prajapati, Sabin
core   +1 more source

The architectural complexity of the human PDC core assembly [PDF]

open access: yes, 2009
The mammalian pyruvate dehydrogenase complex (PDC) is a key multi-enzyme assembly linking the glycolytic pathway to the TCA cycle via the specific conversion of pyruvate to acetyl CoA and, as such, is responsible for the maintenance of glucose ...
Vijayakrishnan, Swetha
core   +1 more source

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