Analysis of genetic mutations using a recombinant model of the mammalian pyruvate dehydrogenase complex [PDF]
The human mitochondrial pyruvate dehydrogenase complex (PDC) is a vital metabolic assembly that controls the key committed step in aerobic carbohydrate utilisation and energy production and as such is responsible for overall glucose homeostasis in man ...
Singh, Geetanjali
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Protein-protein interactions within the 2-oxoacid dehydrogenase complexes [PDF]
The 2-oxoacid dehydrogenase complexes; pyruvate dehydrogenase (PDC), 2- oxoglutarate dehydrogenase (OGDC) and branch-chain 2-oxoacid dehydrogenase (BCOADC), are mitochondrial multienzyme complexes which comprise of multiple copies of three different ...
Richards, Susan Diane
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Immunological and biosynthetic studies of the human pyruvate dehydrogenase complex [PDF]
The human pyruvate dehydrogenase multi-enzyme complex (PDC) catalyses the oxidative decarboxylation of pyruvate, transferring the resultant acetyl group to coenzyme A.
Al-Amodi, Hiba Saeed Bagader
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Regulatory roles of copper metabolism and cuproptosis in human cancers. [PDF]
Wang Z+8 more
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Magnetic resonance and fluorescence studies on pyruvate dehydrogenase complexes and their small molecular weight constituents [PDF]
The articles presented in this thesis do not describe at first glance one well-defined subject. They are, however, in fact connected by one central theme: the study of large enzyme aggregates by molecular physical methods.
Grande, H.J.
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Constructing a recombinant model of the human pyruvate dehydrogenase complex [PDF]
The human pyruvate dehydrogenase complex (PDC) is a large macromolecular assembly involved in the oxidative decarboxylation of pyruvate yielding acetyl CoA as the end product of this reaction, which subsequently enters the tricarboxylic acid (TCA) cycle.
Brown, Audrey Elaine
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Studies on 2-oxoacid dehydrogenase multienzyme complexes of Azotobacter vinelandii [PDF]
In this thesis, some studies on the pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase multienzyme complexes of Azotobacter vinelandii are described; the emphasis strongly lies on the pyruvate dehydrogenase complex.A survey of the literature on 2 ...
Bosma, H.J.
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The Production of Pyruvate in Biological Technology: A Critical Review. [PDF]
Yuan W+8 more
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The 2-Oxoacid Dehydrogenase Multienzyme Complex from Thermophilic Archaea [PDF]
The 2-oxoacid dehydrogenase multienzyme complexes (OADHCs) catalyse the following reaction: 2-Oxoacid + NAD+ + CoASH -> Acyl-SCoA + CO2 + NADH + H+ These 5-10 MDa complexes comprise multiple copies of three enzymes: El, E2, and E3 .
Marrott, Nia
core
Discovery of a second citric acid cycle complex. [PDF]
Roosterman D, Cottrell GS.
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