The Amidase Domain of Lipoamidase Specifically Inactivates Lipoylated Proteins In Vivo [PDF]
, 2009 BACKGROUND:In the 1950s, Reed and coworkers discovered an enzyme activity in Streptococcus faecalis (Enterococcus faecalis) extracts that inactivated the Escherichia. coli and E. faecalis pyruvate dehydrogenase complexes through cleavage of the lipoamide
AA Herbert +35 more
core +3 more sources
Structural and biophysical characterization of human pyruvate dehydrogenase multi-enzyme complex [PDF]
, 2016 Pyruvate dehydrogenase multi-enzyme complex (PDHc) is an assembly of multiple copies of four different proteins. Together they carry out the oxidative decarboxylation of pyruvate and generate acetyl-CoA and NADH, which are components of Krebs cycle ...
Prajapati, Sabin
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Einfluss der alpha-Liponsäure auf die Insulinsensitivität und Glucoseeffektivität bei Patienten mit Diabetes mellitus 2 : eine Untersuchung mit der Minimal-Modeling-Technik [PDF]
, 2003 In dieser klinischen Studie wurden 10 normalgewichtige und 10 übergewichtige Patienten mit Diabetes mellitus 2 und einer unbehandelten diabetischen Polyneuropathie über vier Wochen mit a-Liponsäure 1200 mg/die per os behandelt.
Assadkhani, Afsaneh
core
Carbon source feeding strategies for recombinant protein expression in Pichia pastoris and Pichia methanolica [PDF]
, 2012 Pichia pastoris and Pichia methanolica have been used as expression systems for the production of recombinant protein. The main problems of the production are the slow hierarchic consumption of ethanol and acetate which cause toxicity problems due to ...
Barrera-Avellaneda, LA +3 more
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The architectural complexity of the human PDC core assembly [PDF]
, 2009 The mammalian pyruvate dehydrogenase complex (PDC) is a key multi-enzyme assembly linking the glycolytic pathway to the TCA cycle via the specific conversion of pyruvate to acetyl CoA and, as such, is responsible for the maintenance of glucose ...
Vijayakrishnan, Swetha
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Analysis of genetic mutations using a recombinant model of the mammalian pyruvate dehydrogenase complex [PDF]
, 2008 The human mitochondrial pyruvate dehydrogenase complex (PDC) is a vital metabolic assembly that controls the key committed step in aerobic carbohydrate utilisation and energy production and as such is responsible for overall glucose homeostasis in man ...
Singh, Geetanjali
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Protein-protein interactions within the 2-oxoacid dehydrogenase complexes [PDF]
, 1999 The 2-oxoacid dehydrogenase complexes; pyruvate dehydrogenase (PDC), 2- oxoglutarate dehydrogenase (OGDC) and branch-chain 2-oxoacid dehydrogenase (BCOADC), are mitochondrial multienzyme complexes which comprise of multiple copies of three different ...
Richards, Susan Diane
core
The study of two genes involved in the maintenance of intracellular redox potentials in Thiobacillus ferrooxidans [PDF]
, 1996 Bibliography: p. 128-155.The thioredoxin and ϒ-glutamylcysteine synthetase genes of Thiobacillus ferrooxidans were isolated by complementation of an Escherichia coli trxA gshA double mutant for growth on minimal medium lacking glutathione.
Powles, Rosamund Eira
core
The Journal of biological chemistry, 1989 Treatment of the dihydrolipoyl transacetylase-protein X-kinase subcomplex (E2-X-KcKb) with protease Arg C selectively converted protein X into an inner domain fragment (Mr approximately equal to 35,000) and an outer (lipoyl-bearing) domain fragment (Mr approximately equal to 15,500).
M, Rahmatullah +3 more
openaire +1 more source
Regulatory roles of copper metabolism and cuproptosis in human cancers. [PDF]
Front Oncol, 2023 Wang Z +8 more
europepmc +1 more source