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ENZYMATIC DECARBOXYLATION OF 2,6- AND 2,3-DIHYDROXYPHENYLALANINE
Canadian Journal of Biochemistry and Physiology, 1954 The action of dihydroxyphenylalanine (dopa) decarboxylase of guinea pig kidney and of tyrosine decarboxylase of Streptococcus faecalis R on 2,3- and 2,6-dopa has been studied. Compared with 3,4-dopa, these substrates are decarboxylated by the kidney enzyme at rates decreasing in the order: 2,3-, 3,4-, 2,6-dopa.openaire +2 more sourcesADMINISTRATION OF DIHYDROXYPHENYLALANINE TO PARKINSONIAN PATIENTS.
Canadian Medical Association journal, 1996 Dihydroxyphenylalanine (dopa), the metabolic precursor of dopamine, was administered to 10 parkinsonian patients in oral doses of 1-5 g. and intravenous doses of 0.2-0.5 g. Increases in dopamine excretion of 100- to 1000-fold following the dopa administration indicated that dopa was being absorbed and metabolized. Only two of the 10 patients showed any P L, MCGEER, L R, ZELDOWICZopenaire +1 more sourcel-3,4-Dihydroxyphenylalanine
2010 Nicola Simola, Micaela Morelli, Tooru Mizuno, Suzanne H. Mitchell, Harriet de Wit, H. Valerie Curran, Celia J. A. Morgan, Stephan G. Anagnostaras, Jennifer R Sage, Stephanie A Carmack, Lawrence H. Price, Grasielle C Kincheski, Leandro J Bertoglio, Antonio Padua Carobrez, Andrea Bari, Roshan Cools, Yogita Chudasama, Stefan Leucht, Yogita Chudasama, William Breitbart, Yesne Alici, Karl Mann, Falk Kiefer, Yesne Alici, William Breitbart, Michael M Morgan, M J Christie, Istvan Bitter, Eileen M. Joyce, Jonathan P Roiser, Darren R Christensen, Warren K. Bickel, Kenneth J. Rhodes, Peter Paul De Deyn, Debby Van Dam, Darrel J. Pemberton, Johannes Mosbacher, Thomas Steckler, Alyson J Bond, Alex Hofer, Stefan Leucht, Daniel Bertrand, Hans Rollema, Raymond S Hurst, Irwin Lucki, Fadi T. Maalouf, David A. Brent, David A. Brent, Fadi Maalouf, Alex Hofer, Daniel Bertrand, Hans Rollema, Raymond S Hurst, Huaiyu Yang, George I. Papakostas, Andrew Young, Gabriele Fischer, Annemarie Unger, Linda P Spear, Linda P Spear, Mohammed Shoaib, Emma Childs, Britta Hahn, Peter Boeijinga, Martine Cador, David S Tait, Verity J. Brown, Martine Cador, David Baldwin, Yavin Shaham, Sunila G Nair, Yavin Shaham, Sunila G Nair, Matthew I Palmatier, Rick A Bevins, Peter Riederer, Siegfried Hoyer, Mark Geyer, Anthony Absalom, David Menon, Joseph Zohar, Stephen C Fowler, James Winslow, Kim Wolff, Bankole A. Johnson, Martina de Zwaan, Alyson J Bond, Angela Roberts, Anthony R Isles, Lawrence S. Wilkinson, Anthony R Isles, Lawrence S. Wilkinson, Rosa M M de Almeida, Klaus A. Miczek, Eric Nestler, Naheed (Max) Mirza, Bankole A Johnson, Joseph H Friedman, István Bitter, Michael Minzenberg, Lawrence H. Price, Ashwini Padhi, Naomi Fineberg, Michael M Morgan, MacDonald J. Christie, Lawrence H. Price, Joris C. Verster, Bernard Le Foll, Marilyn E Carroll, Peter A Santi, Ronald F Mucha, Ian P. Stolerman, Richard W Foltin, Michael Minzenberg, Christoph Hiemke, Luis Stinus, Stéphanie Caillé, Martine Cador, Yavin Shaham, John R Mantsch, Ronald F Mucha, Kim Wolff, Anthony L. Riley, Steve Kohut, Brian E. Leonard, Joseph Zohar, R. Andrew Chambers, Gail Winger, Mei-Chuan Ko, James H Woods, Huaiyu Yang, George I. Papakostas, Michael M Morgan, MacDonald J. Christie, Seiya Miyamoto, Thomas R. E. Barnes, Kieran O’Malley, Luis Stinus, Stéphanie Caillé, Martine Cador, David J. Hellerstein, Thomas R. E. Barnes +141 moreopenaire +1 more source