Results 341 to 350 of about 24,273 (376)

3,4-dihydroxyphenylalanine-assisted hydroxyapatite nanoparticle coating on polymer scaffolds for efficient osteoconduction.

Tissue Engineering. Part C, Methods, 2012
For bone regeneration applications, scaffolds made from a composite of a biodegradable polymer and ceramic have advantages over scaffolds made from only one component (biodegradable polymer or ceramic alone).
H. Yang, JooYeon Park, Wan-Geun La, Hyeon-Ki Jang, Minhyung Lee, Byung-Soo Kim   +5 more
semanticscholar   +1 more source

A method for the determination of 3,4-dihydroxyphenylalanine (DOPA) in brain

Naunyn-Schmiedeberg's Archives of Pharmacology, 1972
The method is an extension of the chromatographic separation procedure for 5-HIAA and 5-HTP published by Lindqvist (1971). Brain tissue is extracted with perchloric acid. After adjustment of the pH to 2 the extract is passed through a Dowex 50W, X-4 column.
Wolfgang Kehr, Arvid Carlsson, Margit Lindqvist   +2 more
openaire   +3 more sources

Stability of collagen in the presence of 3,4-dihydroxyphenylalanine (DOPA)

Journal of Photochemistry and Photobiology B: Biology, 2009
Many cross-linking agents for collagen are available with varying levels of toxicity and some are in use in biomedical implants of collagen. L-DOPA (3,4-dihydroxyphenylalanine), a neurotransmitter, is a naturally present compound in the living system and is the target in therapeutic strategy of Parkinson's disease.
R. Usha, A. Rajaram, T. Ramasami
openaire   +3 more sources

Radical sequestration by protein-bound 3,4-dihydroxyphenylalanine

The International Journal of Biochemistry & Cell Biology, 2010
Protein-bound 3,4-dihydroxyphenylalanine (PB-DOPA), a redox-active product of protein oxidation, is capable of functioning as both a pro- and antioxidant. A number of in vitro and in vivo studies have demonstrated a toxic, non-toxic or even beneficial effect of free DOPA, however little investigation has examined the physiological activity of PB-DOPA ...
Nelson, Michelle, Foxwell, Alice R., Tyrer, Peter, Dean, Roger T.   +3 more
openaire   +4 more sources

The fluorescence of dihydroxyphenylalanine: the effects of protonation-deprotonation

Coloration Technology, 1999
The fluorescence excitation and emission spectra and quantum yields of 3,4‐dihydroxyphenylalanine (DOPA), its methyl ester (DOPAM) and the N‐acetylated derivative (DOPANA) in aqueous solution at pH values ranging from 3.0 to 10.0 have been determined and the excitation spectra related to their absorption spectra.
openaire   +2 more sources

Iron‐Mediated Oxidation of 3,4‐Dihydroxyphenylalanine to an Excitotoxin

Journal of Neurochemistry, 1995
Abstract: 2,4,5‐Trihydroxyphenylalanine (TOPA) oxidizes in solution to form a quinone derivative that is a non‐NMDA glutamatergic agonist and neurotoxin. DOPA can autoxidize in physiological solutions to form small amounts of both TOPA and TOPA quinone.
Elias Aizenman, Timothy A. Newcomer, Paul A. Rosenberg   +2 more
openaire   +3 more sources

Dityrosine, 3,4-dihydroxyphenylalanine (DOPA), and radical formation from tyrosine residues on milk proteins with globular and flexible structures as a result of riboflavin-mediated photo-oxidation.

Journal of Agricultural and Food Chemistry, 2011
Riboflavin-mediated photo-oxidative damage to protein Tyr residues has been examined to determine whether protein structure influences competing protein oxidation pathways in single proteins and protein mixtures.
T. Dalsgaard, J. Nielsen, Bronwyn E. Brown, Nadina Stadler, M. Davies   +4 more
semanticscholar   +1 more source

L-3,4-dihydroxyphenylalanine-collagen modified PDMS surface for controlled cell culture

, 2012
The modification of the poly(dimethylsiloxane) (PDMS) surface for improved wettability and biocompatibility has been a hot topic for its biological applications.
C. Gao, Yuanyuan Guo, Jia He, Ming Wu, Yang Liu, Zhongshan Chen, W. Cai, Yanlian Yang, Chen Wang, Xizeng Feng   +9 more
semanticscholar   +1 more source

The fluorescent oxidation products of dihydroxyphenylalanine and its esters

Journal of Photochemistry and Photobiology B: Biology, 2000
Dihydroxyphenylalanine (DOPA), its methyl ester (DOPAM) and the N-acetylated derivative of the ester (DOPAMNA) are found to undergo rapid oxidation in air-saturated alkaline solution. Some of the products of oxidation exhibit fluorescent emission in the 300-500 nm spectral range and their excitation-emission spectra have been determined in acidic and ...
Gerald J. Smith, Timothy G. Haskell
openaire   +3 more sources

Chiral gold nanoparticle-based electrochemical sensor for enantioselective recognition of 3,4-dihydroxyphenylalanine.

Chemical Communications, 2010
The enantioselective recognition of 3,4-dihydroxyphenylalanine using penicillamine-modified gold nanoparticles has been investigated. Smaller gold nanoparticles with one enantiomeric ligand facilitate the redox reaction of only one enantiomer of 3,4 ...
Yeon-Joo Kang, Jeong‐Wook Oh, Yang‐Rae Kim, Jong Seung Kim, Hasuck Kim   +4 more
semanticscholar   +1 more source