Results 351 to 360 of about 24,273 (376)

Identification of 3,4-dihydroxyphenylalanine as tyrosinase cofactor in melanoma

Biochemical and Biophysical Research Communications, 1966
The tyrosine hydroxylase activity of tyrosinase from hamster melanoma requires a reduced co-substrate. The most efficient co-substrate for in vitro experiments was shown to be L-3,4-dihydroxyphenylalanine (dopa) (Pomerantz, 1964, 1966); only a catalytic amount of dopa was required because it is also a product of the hydroxylation (Equation (1)).
Margaret C. Warner, Seymour H. Pomerantz
openaire   +2 more sources

Positron emission tomography/computed tomography diagnostics by means of fluorine-18-L-dihydroxyphenylalanine in congenital hyperinsulinism.

Seminars in Pediatric Surgery, 2011
The unfavorable prognosis of congenital hyperinsulinism (CHI) can be avoided if the patients are treated with high-dose glucose infusions and timely surgical intervention. Circumscribed foci used to be identified by selective percutaneous pancreatic vein
W. Mohnike, W. Barthlen, K. Mohnike, O. Blankenstein   +3 more
semanticscholar   +1 more source

Does 3,4-Dihydroxyphenylalanine Play a Part in Favism?

Nature, 1967
FAVISM is a haemolytic anaemia precipitated in some glucose-6-phosphate dehydrogenase (G-6-PD) deficient individuals by the ingestion of fava beans. Although the mechanism of haemolysis in G-6-PD deficient individuals has not been elucidated, it is generally thought that the destruction of reduced glutathione (GSH) is associated with the events which ...
Edward M. Kosower, Nechama S. Kosower
openaire   +3 more sources

Bioconjugation of L-3,4-dihydroxyphenylalanine containing protein with a polysaccharide.

Bioconjugate chemistry, 2011
We describe the simple bioconjugation strategy in combination of periodate chemistry and unnatural amino acid incorporation. The residue specific incorporation of 3,4-dihydroxy-l-phenylalanine can alter the properties of protein to conjugate into the ...
N. Ayyadurai, N. S. Prabhu, K. Deepankumar, Y. Jang, Nataraj Chitrapriya, E. Song, Nahum Lee, Seog K. Kim, Byung-Gee Kim, N. Soundrarajan, Sun-Gu Lee, H. Cha, N. Budisa, Hyungdon Yun   +13 more
semanticscholar   +1 more source

The synthesis and adhesive performance of the poly(N-benzyloxycarbonyl-3,4-dihydroxyphenylalanine) derived from 3,4-dihydroxyphenylalanine

Journal of Adhesion Science and Technology, 2013
Adhesive polymers, which contain an unusual amino acid, 3,4-dihydroxyphenylalanine (DOPA), can bind strongly to all organic or inorganic surfaces. However, due to DOPA’s poor solubility in organic solvents, it is difficult for us to get desired adhesive polymers. In this paper, poly(N-benzyloxycarbonyl-3,4-dihydroxyphenylalanine) (PNBD) was synthesized
Yi Zhong, Yihang Lv, Hong Xu, Dongdong Gao, Zhiping Mao, Hui Ma   +5 more
openaire   +2 more sources

THE EXCRETION OF DIHYDROXYPHENYLALANINE, DOPAMINE, AND DIHYDROXYPHENYLACETIC ACID IN NEUROBLASTOMA

Pediatrics, 1963
Six cases of neuroblastoma and one of ganglioneuroma were studied with respect to excretion of dopamine and dopac (3,4-dihydroxyphenylacetic acid) in the urine. The quantities of these compounds were found to reflect the clinical status of the patient. In general, they were low during remission and increased just before and during relapse. In the urine
T L, SOURKES, R L, DENTON, G F, MURPHY, B, CHAVEZ, S, SAINT CYR   +4 more
openaire   +2 more sources

Biosynthesis of 3,4-dihydroxyphenylalanine in Vicia faba

Phytochemistry, 1973
Abstract Radioactive shikimic acid and l -tyrosine were shown to be efficient precursors of 3,4-dihydroxyphenylalanine (DOPA) in Vicia faba . [1- 14 C]Acetate and l [U- 14 C]phenylalanine were not incorporated into tyrosine or DOPA. Thus the synthesis of DOPA occurs via the shikimic acid pathway and tyrosine or a very closely related metabolise ...
Eric E. Conn, Thomas Griffith
openaire   +2 more sources

ENZYMATIC DECARBOXYLATION OF 2,6- AND 2,3-DIHYDROXYPHENYLALANINE

Canadian Journal of Biochemistry and Physiology, 1954
The action of dihydroxyphenylalanine (dopa) decarboxylase of guinea pig kidney and of tyrosine decarboxylase of Streptococcus faecalis R on 2,3- and 2,6-dopa has been studied. Compared with 3,4-dopa, these substrates are decarboxylated by the kidney enzyme at rates decreasing in the order: 2,3-, 3,4-, 2,6-dopa.
openaire   +3 more sources

Excretion of 3,4-dihydroxyphenylalanine in urine

Biochimica et Biophysica Acta (BBA) - General Subjects, 1961
Theo Gerritsen, Harry A. Waisman, Stephen C. Copps   +2 more
openaire   +3 more sources

Remission in dihydroxyphenylalanine‐responsive dystonia

Movement Disorders, 1995
M. Di Capua, Enrico Bertini
openaire   +3 more sources