Results 191 to 200 of about 49,544 (290)

Intranuclear localisation of KLF3‐AS1 under the balance of histone acetylation and methylation in BMSCs ameliorates cerebral ischaemia‒reperfusion injury by preserving microglial mitochondrial function and inhibiting inflammatory polarisation

open access: yesClinical and Translational Medicine, Volume 16, Issue 11, November 2026.
Epigenetic activation of KLF3‐AS1 in BMSCs, characterised by increased H3K27 acetylation and decreased H3K27 trimethylation at its promoter, enhances BMSC viability, proliferation and migration. Exosomal KLF3‐AS1 is delivered to microglia, which mechanistically promotes ETV4 nuclear translocation to activate SIRT3 transcription, preserving microglial ...
Qian Li   +4 more
wiley   +1 more source

Support‐Driven Hydrogen Migration Enhances Ammonia Decomposition in Direct Ammonia Protonic Ceramic Fuel Cells

open access: yesENERGY &ENVIRONMENTAL MATERIALS, Volume 9, Issue 6, November 2026.
Enhanced hydrogen species migration enabled by FN/BZY catalyst mitigates intermediate accumulation and improves DA‐PCFC performance during ammonia decomposition. Ammonia, with its high hydrogen density and carbon‐free nature, serves as ideal fuel for direct ammonia protonic ceramic fuel cells (DA‐PCFCs).
Meijuan Fei   +9 more
wiley   +1 more source

The Role of Mitochondrial Homeostasis in the Pathogenesis of Chronic Rhinosinusitis

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 11, November 2026.
The vicious cycle between pathogenic factors‐induced inflammation, oxidative stress, and mitochondrial dysfunction in the context of chronic rhinosinusitis. Created in BioRender. Taghizadeh‐Hesary (2026) https://BioRender.com/k5f4t1f. ABSTRACT Background Chronic rhinosinusitis (CRS) is a common clinical condition characterized by persistent ...
Babak Ghalehbaghi   +6 more
wiley   +1 more source

Late INa as a Therapeutic Target: New Strategies, Computational Modelling, Drug Development, and Clinical Translation

open access: yesMedicinal Research Reviews, Volume 46, Issue 6, Page 1939-1957, November 2026.
ABSTRACT The Nav1.5 channel, a major isoform of voltage‐gated sodium ion channel, is mainly found in ventricular cardiomyocytes, playing a key role in generating essential cardiac action potentials for normal heart rhythms. Mutations in Nav1.5 have been associated with severe heart conditions such as long QT syndrome, Brugada syndrome, cardiac ...
Arkapravo Chattopadhyay   +3 more
wiley   +1 more source

DIY

open access: yesIndústrias Culturais, 2005
openaire   +1 more source

Rapid and Efficient Affinity Isolation of Engineered Extracellular Vesicles Encapsulating Functional Proteins via Internal Twin‐Strep Tetraspanin Tagging

open access: yesSmall, Volume 22, Issue 62, 6 November 2026.
Structure‐guided internal twin‐Strep tagging of the tetraspanins CD63 or CD9 enables rapid and efficient antibody‐free affinity isolation of engineered extracellular vesicles (EVs) using Strep technology while allowing luminal protein loading. The approach removes over 96% of contaminants, separates tagged EVs from coexisting viral particles, and ...
Minh‐Tu Pham   +14 more
wiley   +1 more source

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