Results 31 to 40 of about 225,852 (174)

Phase I study of dose escalation to dominant intraprostatic lesions using high-dose-rate brachytherapy. [PDF]

open access: yes, 2018
PurposeRadiation dose escalation for prostate cancer improves biochemical control but is limited by toxicity. Magnetic resonance spectroscopic imaging (MRSI) can define dominant intraprostatic lesions (DIL).
Braunstein, Steve E   +9 more
core  

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

Türkiye Kentlerinin Kentleşme Düzeylerinin Demografik, Ekonomik ve Sosyal Değişkenlerle Belirlenmesi

open access: yesCoğrafi Bilimler Dergisi, 2008
The fundamental economic restructuring driven by globalisation and the revolution in information and communication technology are the most important processes in our contemporary world.
M. Murat Yüceşahin, E. Murat Özgür
doaj   +1 more source

NPM1 Mediates mRNA Sorting into Extracellular Vesicles via Specific RNA Motif Binding and Phase Separation

open access: yesAdvanced Science, EarlyView.
NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang   +8 more
wiley   +1 more source

Ege Bölgesi’nde yağışın mekânsal dağılımı

open access: yesCoğrafi Bilimler Dergisi, 2013
Spatial modelling of climatological variables is one of the most crucial parts of environmental studies. Prediction of natural events such as hydrological phenomenon, drought, flood, ground-surface water amount, pollution of water sources, and issues ...
Olgu Aydın, İhsan Çiçek
doaj   +1 more source

Investigating Exponential and Geometric Polynomials with Euler-Seidel Algorithm [PDF]

open access: yes, 2010
In this paper we use Euler-Seidel matrices method to find out some properties of exponential and geometric polynomials and numbers.
Dil, Ayhan, Kurt, Veli
core  

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan   +17 more
wiley   +1 more source

Kula Meryem Ana Kilisesi Karamanlıca Mezar Taşları

open access: yesBelleten, 2016
Kula’da Meryem Ana Kilisesi’nin yakın zamandaki restorasyonu sırasında bulunan bazı mezar taşları Karamanlıca olarak tabir edilen Yunan (Grek) harfli Türkçe metinlere sahiptir.
Rüstem Bozer, Serkan Sunay
doaj   +1 more source

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

open access: yesAdvanced Science, EarlyView.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen   +13 more
wiley   +1 more source

Nutritional Sustainability Inside–Marketing Sustainability as an Inherent Ingredient

open access: yesFrontiers in Nutrition, 2019
Current discussions about the concept of nutritional sustainability show a high complexity of this topic leading to many different definitions. Regarding communication issues of nutritional sustainability between actors of food chains this complexity ...
Sabine Bornkessel   +3 more
doaj   +1 more source

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