Results 71 to 80 of about 67,476 (263)

Engineered Exosomal miR‐146a‐5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid‐Induced Osteonecrosis of Femoral Head

Advanced Science, EarlyView.
Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv, Xuejie Cai, Yiming Xu, Xingdong Yang, Ruoying Wang, Han Wang, Yixin Bian, Jiawei Xu, Jiao Lu, Lulu Liu, Yingjie Wang, Jibin Song, Bin Feng, Xisheng Weng   +13 more
wiley   +1 more source

Impact of Four Different Chlorella vulgaris Strains on the Properties of Durum Wheat Semolina Pasta

Applied Sciences
Microalgae are a promising protein source due to their high protein content; high reproductivity; and low carbon, water, and arable land footprints.
Marie-Christin Baune, Thomas Lickert, Frank Schilling, Ute Bindrich, Igor Tomasevic, Volker Heinz, Sergiy Smetana, Nino Terjung   +7 more
doaj   +1 more source

Tumor‐Specific Delivery of CD28 siRNA via Lyso‐PC C‐16 Modified Lipid Nanoparticles Overcomes Anti‐PD‐1 Resistance by Remodeling Tumor Microenvironment

Advanced Science, EarlyView.
This study develops 16:0 LPC‐modified lipid nanoparticles (LPC‐LNPs) with cancer cell specificity by exploiting altered tumor lipid metabolism. LPC‐LNPs encapsulating Cd28 small interfering RNA (LPC‐LNP‐Cd28) knock down cancer cell CD28 without affecting T cells, inflame the tumor microenvironment, and overcome anti‐PD‐1 resistance.
Yangyang Chai, Keyu Wang, Jiali Fang, Shaorui Jia, Yansong Shi, Wanfeng Gao, Xinpeng Liu, Jiaqiang Li, Zenghui Cui, Yazhi Qian, Xiaosu Chen, Dan Ding, Xuetao Cao   +12 more
wiley   +1 more source

İnsan İskeletlerinde Foramen Magnum'dan Cinsiyet Tayini

Ankara Üniversitesi Dil ve Tarih-Coğrafya Fakültesi Dergisi, 2003
Antropoloji ve adli bilimlerde erişkin insan iskeletlerinin cinsiyetinin belirlenmesi çok önemlidir. Erişkinlerde cinsiyet farklılıkları iyi bir şekilde belirlenmekte ve cinsiyet determinasyonu güvenle yapılabilmektedir.
Erksin Güleç, Mehmet Sağır, İsmail Özer   +2 more
doaj  

Homologous membrane wrapped ZIF‐8 nanoparticles accelerate differentiation of neural stem cell for spinal cord injury therapy

BMEMat, EarlyView.
Homologous membrane wrapped ZIF‐8 nanoparticles were proposed to improve biocompatibility and targeting ability to neural stem cells (NSCs). ZIF‐8‐SCM NPs exhibit pH responsiveness, thereby generating an intracellular Zn2+ storm to accelerate neural differentiation through calcium and MAPK signaling pathways. Moreover, they promote function recovery in
Jie Wang, Lusen Shi, Xinhui Liu, Zhong Zhuang, Zhichao Feng, Chunhui Sun, Jingang Wang, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Shuping Wang, Hengxing Zhou, Na Ren   +11 more
wiley   +1 more source

Direct Capture of Dynamic Surface Reconstruction in a Perovskite Cathode via Operando Raman Spectroscopy

Carbon Energy, EarlyView.
Operando Raman spectroscopy directly captures the dynamic form conditions of the BaCoO3‐δ phase on the BSCY surface. This observation provides critical insight into the phase evolution mechanisms, which are essential for optimizing the performance and stability of BSCY‐based protonic ceramic fuel cell cathodes.
Yongxin Li, Wenhuai Li, Wenxin Liu, Chang Li, Yu Li, Zhaohui Cai, Chuan Zhou, Jie Miao, Huangang Shi, Wei Zhou, Zongping Shao   +10 more
wiley   +1 more source

TÜRKİYE’DE ŞEHİRLEŞMENİN MEKANSAL DAĞILIŞI ve DEĞİŞİMİ

Coğrafi Bilimler Dergisi, 2004
Spatial distribution of urbanization and its change that reflecting to three time crosssections during Republican Period of Turkey is taking into consideration in this article.
M. Murat YÜCEŞAHİN, Rüya BAYAR , E.Murat ÖZGÜR   +2 more
doaj   +1 more source

Modeling of Color and Degradation of C‐Phycocyanin Extracted From Arthrospira platensis and Chlorogloeopsis HTF

Chemie Ingenieur Technik, EarlyView.
A nonlinear kinetic model was developed and successfully implemented, which describes the degradation of the protein C‐phycocyanin depending on temperature and pH value. C‐phycocyanin had been extracted from two different cyanobacteria. In addition to protein degradation, the fading of the typical blue color of this protein was included in the model ...
Martina Kießling, Knut Franke, Viggó Marteinsson, René Groben, Volker Heinz, Kemal Aganovic   +5 more
wiley   +1 more source

Etkileşim temelli dil müdahale programının geliştirilmesi ve gecikmiş dil-konuşması olan çocuklarda etkililiğinin incelenmesi [PDF]

, 2021
Gecikmiş dil ve konuşma, tanılanmış herhangi bir bozukluk ya da bilişsel, motor gelişimle ilgili bir yetersizlik bulunmamasına rağmen dilin geç edinimi olup okul öncesi dönemde oldukça sık görülmektedir. Ülkemizde gecikmiş dil ve konuşması olan çocuklara

core  

Türk Dil Kurumu’nun Süreli Yayınlar Veri Tabanı’ndaki sinema terimlerinin oluşturulma yöntemleri üzerine bir inceleme

, 2023
Terim ve terim oluşturma yöntemlerine dair sorunları çözmek için çoğu dilbilimci ve alanında uzman terimbilimciler tarafından birçok çalışmanın gerçekleştirildiği söylenebilir.
Onur ÖZCAN, Öz, Sefa, Özcan, Onur, Sefa ÖZ   +3 more
core   +1 more source