Results 131 to 140 of about 146,784 (300)

Critical upward shift of intracranial pressure levels in extremely obese patients; normalization due to bariatric surgery

The Ultrasound Journal
Background Increase in body mass index (BMI) is a risk factor for idiopathic intracranial hypertension (IIH). The matter of body weight and intracranial pressure (ICP) in clinically asymptomatic obese patients is unknown.
Nabil Al Shammas, Robert Luck, Sophie Schumann, Dragana Köhler, Lutz Mirow, Bernhard Rosengarten   +5 more
doaj   +1 more source

Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency

Advanced Science, EarlyView.
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen, Zong Chen, Chenzhi Lai, Yingying Yue, Tian He, Hao Gong, Jing Shi, Xiaoshuang Guo, Yu Wang, Guodong Song, Xiaolei Jin   +10 more
wiley   +1 more source

Impact of stent deployment pressure and poststenting dilatation on the outcome of elective percutaneous coronary intervention

, 2016
Mahmoud K Nour Department of Critical Care Medicine, Faculty of Medicine, Cairo University, Giza, Cairo, Egypt Background: High-pressure stent deployment was proposed as a strategy that ensures complete stent apposition but its relation to outcome is ...
Nour MK
core  

Pancreatic solid pseudopapillary neoplasm: clinical, computed tomography and endoscopic ultrasound features unraveling a rare tumor with pathologic correlation

The Egyptian Journal of Radiology and Nuclear Medicine
Background Solid pseudopapillary neoplasm (SPN) of the pancreas exhibits low malignant potential and is typically curable via surgical excision, with > 90% 5-year survival rates, including metastatic cases.
Fatmaelzahraa Abdelfattah Denewar, Ahmed E. Eladl, Fatma Mohamed Sherif, Omar Abdallah, Elsayed Ghoneem, Khadija Denewar, Eman Fouad Omran, Zainab A. Ramadan   +7 more
doaj   +1 more source

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

Advanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou, Ruixi Yu, Xuan Zhou, Feng Shi, Zeyu Lin, Peng Gao, Lujia Wang, Ninghan Feng, Zhong Wu, Dawei Wang   +9 more
wiley   +1 more source

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

Advanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian, Jia‐Xi Gu, Zhang Yue, Chun‐Ze Yuan, Hai‐Bin Ji, Ao Li, Yu Zhong, Xiu‐Fan Xu, Yu‐Qiu He, Ye‐Fan Jiang, Hong‐Shan Chen, Xiang Chen, Meng‐Lin Chao, Yong‐Feng Shao   +13 more
wiley   +1 more source

Bilateral congenital venous tortuosity and dilatation combined with cilioretinal artery: a photographic essay

, 2016
Nuo Xu,1 Yi Cui,2 Zhonghai Gao1 1Department of Ophthalmology, Fujian Provincial Hospital, 2Department of Ophthalmology, The Union Hospital of Fujian Medical University, Fuzhou City, Fujian Province, People's Republic of China Abstract: To report the
Xu N, Cui Y, Gao Z
core  

The relation between zero-time pretransplant deceased donor renal biopsy and kidney transplant survival

Research and Reports in Urology, 2019
Mahmoud Tavakkoli,1 Masoud Yousefi,2 Reza Mahdavi,2 Mahmoud Reza Kalantari,3 Amin Mirsani,2 Amin Korooji2 1Kidney Transplantation Complications Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; 2Department of Urology, Faculty of ...
Tavakkoli M, Yousefi M, Mahdavi R, Kalantari MR, Mirsani A, Korooji A   +5 more
doaj  

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source