Results 31 to 40 of about 36,061 (316)

Clinicopathologic Features and Magnetic Resonance Imaging Findings in 24 Cats With Histopathologically Confirmed Neurologic Feline Infectious Peritonitis [PDF]

, 2017
Background: Feline infectious peritonitis (FIP) is the most common infectious central nervous system (CNS) disease in the cat and is invariably fatal. Improved means of antemortem diagnosis is required to facilitate clinical decision making.
Bailey, Bradshaw, Foley, Gruendl, Gunn-Moore, Kipar, Laubner, Marioni-Henry, Milhorat, Negrin, Okada, Pedersen, Pedersen, Pedersen, Rand, Schmidt, Tamke, Tani, Tha, Tha, Thomas, Timmann, Tomek, Wisner   +23 more
core   +1 more source

Novel ATP2A2 Gene Mutation c.118G>A Causing Keratinocyte and Cardiomyocyte Disconnection in Darier Disease

Biomedicines
Darier disease (DD) is an autosomal dominant disorder due to pathogenic variants of the ATP2A2 gene that causes an isolated skin manifestation based on keratinocyte disconnection and apoptosis.
Andrea Frustaci, Alessandro De Luca, Romina Verardo, Valentina Guida, Maria Alfarano, Camilla Calvieri, Luigi Sansone, Matteo Antonio Russo, Cristina Chimenti   +8 more
doaj   +1 more source

Papillary in situ and intramucosal adenocarcinoma of the lower third of common bile duct. A report and review of the literature

Annals of Hepatology, 2015
We report the case of a 37-year-old woman with no relevant medical history. She was admitted to the hospital for epigastric pain related with food intake for 4 days; the pain did not improve with symptomatic management. A laparoscopic cholecystectomy due
Eduardo E. Montalvo-Javé, Fredy Chablé-Montero, Liz N. Toapanta-Yanchapaxi, Fernando Rojas-Mendoza, Carlos López-Caballero, Mario L. Roca-Cabrera, Germán E. Mendoza-Barrrera   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Biliary Cystadenocarcinoma Associated with Atrophy of the Left Hepatic Lobe and Hepatolithiasis Mimicking Intrahepatic Cholangiocarcinoma: A Case Report

Kaohsiung Journal of Medical Sciences, 2004
Biliary cystadenocarcinoma and its benign counterpart, biliary cystadenoma, are rare hepatic cystic tumors arising from the hepatobiliary epithelium. We report the case of a 68-year-old Taiwanese woman who presented initially with acute cholangitis.
Chang-An Tseng
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A Case of Esophageal Intramural Pseudodiverticulosis

Gut and Liver, 2011
Esophageal intramural pseudodiverticulosis (EIP) is a rare benign disease that is characterized by multiple tiny flaskshaped outpouching lesions of the esophageal wall. The etiology is unknown, but the pathologic fi ndings include dilatation of excretory
doaj   +1 more source

Inclusion body myositis: therapeutic approaches. [PDF]

, 2012
The idiopathic inflammatory myopathies are a heterogeneous group of diseases that include dermatomyositis (DM), polymyositis (PM), inclusion body myositis (IBM) and other less common myopathies.
Aggarwal, Rohit, Oddis, Chester V
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Understanding heterogeneous mechanisms of heart failure with preserved ejection fraction through cardiorenal mathematical modeling.

PLoS Computational Biology, 2023
In contrast to heart failure (HF) with reduced ejection fraction (HFrEF), effective interventions for HF with preserved ejection fraction (HFpEF) have proven elusive, in part because it is a heterogeneous syndrome with incompletely understood ...
Sanchita Basu, Hongtao Yu, Jonathan R Murrow, K Melissa Hallow   +3 more
doaj   +1 more source