Results 71 to 80 of about 1,590,882 (307)

Understanding the Burden of Orofacial Involvement and Patient Treatment Preferences in Systemic Sclerosis: Results From a Large International Survey

open access: yesArthritis Care &Research, EarlyView.
Objective Orofacial manifestations are significantly impactful in patients with systemic sclerosis (SSc) yet remain understudied, with no dedicated clinical guidelines to inform their management. Methods An international online survey comprised38 questions addressing orofacial manifestations of SSc, including patients’ confidence in their treating ...
Eleni Deligianni   +4 more
wiley   +1 more source

Term pregnancy with choriocarcinoma presenting as severe fetal anemia and postpartum hemorrhage

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2016
Objective: Term pregnancy with choriocarcinoma is a rare condition that can be a serious health threat to both the mother and the fetus. We present a rare case of term pregnancy with choriocarcinoma presenting as severe fetal anemia and postpartum ...
Hsiu-Huei Peng   +4 more
doaj   +1 more source

Beyond Visual Scoring: Computational CT‐analysis for HRCT based quantification of Interstitial Lung Disease in Inflammatory Rheumatic Disease

open access: yesArthritis Care &Research, Accepted Article.
Interstitial lung disease (IRD‐ILD) is a significant cause of morbidity and mortality in patients with inflammatory rheumatic disorders (IRD). High‐resolution computed tomography (HRCT) is widely considered the gold standard for the non‐invasive assessment of ILD; however, its interpretation is constrained by substantial inter‐observer variability and ...
Alexander Pfeil   +7 more
wiley   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz   +9 more
wiley   +1 more source

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

open access: yesAdvanced Healthcare Materials, EarlyView.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi   +10 more
wiley   +1 more source

The Relationship between Opioid Addiction and Diameter of the Common Bile Duct [PDF]

open access: yesPatient Safety and Quality Improvement Journal, 2016
Introduction: According to statistics, opioid addiction is quite common in Iran. Pathologic dilatation of the Common Bile Duct (CBD) may be caused by mechanical obstruction or opioid consumption; the latter is especially common among chronic opium ...
Bita Dadpour   +6 more
doaj  

Ultrasonographic Diagnosis of Diastematomyelia During the 14th Week of Gestation

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2009
Objective: We present a case of type I diastematomyelia diagnosed with ultrasonography at the 14th week of gestation. Case Report: A 26-year-old primigravida at 14 weeks' gestation was presented to our outpatient department with a complaint of dysuria ...
Kazşm Emre Karaşahin   +4 more
doaj   +1 more source

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

open access: yesAdvanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer   +12 more
wiley   +1 more source

Biomechanical investigation of tricuspid valve dynamics and the effect of annuloplasty techniques during acute right ventricle pressure overloadCentral MessagePerspective

open access: yesJTCVS Open
Objective: Current surgical strategy for functional tricuspid regurgitation comprises annular reduction annuloplasty. The substantial recurrence rate points to incomplete understanding of tricuspid valve (TV) -right ventricle (RV) relationship during ...
Margo Vandenheede, MD   +4 more
doaj   +1 more source

Inhibition of VEGF‐Induced Angiogenesis and Vascular Leakage by Bicistronic Co‐Expression of Aflibercept and COMP‐Ang1

open access: yesAdvanced Healthcare Materials, EarlyView.
A bicistronic rAAV8 vector encoding Aflibercept (Afb) and COMP‐cAng1 simultaneously coordinates VEGF clearance and Tie2‐mediated vessel maturation. In a 3D angiogenesis‐on‐a‐chip model, rAAV8‐Afb/cAng1 effectively reverses pathological barrier breakdown under clinical disease‐mimicking challenges.
Bong‐Kyu Kim   +9 more
wiley   +1 more source

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