Results 131 to 140 of about 592,769 (337)

Pathogenic glycosyltransferase genes and potential therapeutic drugs in pressure overload‐induced heart failure

ESC Heart Failure, EarlyView.
Abstract Aims Protein glycosylation regulated by glycosyltransferases is an important type of post‐translational modification. The role of the glycosyltransferase genes (GTGs) in heart failure (HF) remains unclear and requires further investigation.
Jiahe Wu, Yi Lu, Xinchen Gao, Xiaorong Hu, Zhibing Lu, Chenze Li   +5 more
wiley   +1 more source

Cell therapy in dilated cardiomyopathy: from animal models to clinical trials

Brazilian Journal of Medical and Biological Research, 2011
Dilated cardiomyopathy can be the end-stage form and common denominator of several cardiac disorders of known cause, such as hypertensive, ischemic, diabetic and Chagasic diseases.
C. del Corsso, A.C. Campos de Carvalho
doaj   +2 more sources

Homozygous truncating mutation in NRAP gene identified by whole exome sequencing in a patient with dilated cardiomyopathy

Scientific Reports, 2017
The genetic background of dilated cardiomyopathy is highly heterogeneous, with close to 100 known genes and a number of candidates described to date.
Grażyna T. Truszkowska, Zofia T. Bilińska, Angelika Muchowicz, Agnieszka Pollak, Anna Biernacka, Katarzyna Kozar-Kamińska, Piotr Stawiński, Piotr Gasperowicz, Joanna Kosińska, Tomasz Zieliński, Rafał Płoski   +10 more
doaj   +1 more source

Catheter Ablation of Ventricular Tachycardia and Mortality in Patients With Nonischemic Dilated Cardiomyopathy [PDF]

, 2015
Borislav Dinov, Arash Arya, Alexandra Schratter, Valentina Schirripa, Lukas Fiedler, Philipp Sommer, Andreas Bollmann, Sascha Rolf, Christopher Piorkowski, Gerhard Hindricks   +9 more
openalex   +1 more source

Risk Stratification for Sudden Cardiac Death In Patients With Non-ischemic Dilated Cardiomyopathy [PDF]

, 2005
Non ischemic dilated cardiomyopathy (NIDCM) is a disorder of myocardium. It has varying etiologies. Albeit the varying etiologies of this heart muscle disorder, it presents with symptoms of heart failure, and rarely as sudden cardiac death (SCD ...
Ghosh, Joydeep, Greenberg, Yisachar, Shekha, Karthik, Thekkoott, Deepak   +3 more
core   +1 more source

Re‐PERFUSE: Phase 1b study of AZD3427, a novel relaxin receptor agonist, on renal perfusion in HFrEF patients

ESC Heart Failure, EarlyView.
Abstract Aims Renal impairment frequently coexists with heart failure (HF) and is associated with increased risk of poor clinical outcomes. This highlights the urgent need for therapies targeting both cardiac and renal dysfunction. AZD3427, a long‐acting recombinant fusion protein and relaxin analogue that selectively activates the relaxin family ...
Marcin Ufnal, Macarena P. Quintana‐Hayashi, Kathleen Connolly, Daniel Pettersen, Zsolt Cselényi, Aurelija Jucaite, Magnus Schou, Andrea Varrone, Melanie Chan, Lars H. Lund   +9 more
wiley   +1 more source

Exploring the Crosstalk Between LMNA and Splicing Machinery Gene Mutations in Dilated Cardiomyopathy [PDF]

, 2018
Hind C. Zahr, Diana E. Jaalouk
openalex   +1 more source

Percutaneous endocardial alginate–hydrogel injection in the treatment of heart failure: First‐in‐human study

ESC Heart Failure, EarlyView.
Using EndoWings™ and XDROP™, we developed a percutaneous minimally invasive technique for sequential circumferential alginate hydrogel injection into LV free mid‐wall. This human study assessed its safety/feasibility in HFrEF patients, with personalised biomechanical models.
Bo Wang, Shuo Wang, Chao Gao, D. Scott Lim, Rutao Wang, Xin Meng, Ying Liu, Cun‐jun Zhu, Yoshinobu Onuma, Yunbing Wang, Patrick W.J.C. Serruys, Runlin Gao, Randall J. Lee, Ling Tao   +13 more
wiley   +1 more source

Kardiomiopatia rozstrzeniowa i przerostowa u płodu matki z cukrzycą ciężarnych - opis przypadku [PDF]

Pediatric Endocrinology, Diabetes and Metabolism, 2010
There is an increased risk of a hypertrophic cardiomyopathy and congenital heart defects among newborns of diabetic mothers. We report a case of hypertrophic cardiomyopathy preceded with dilated cardiomyopathy in a fetus of a diabetic mother.
Monika Kwiatek, Jerzy Węgrzynowski, Grażyna Dawid, Anita Horodnicka-Józwa, Elżbieta Petriczko, Agnieszka Biczysko-Mokosa   +5 more
doaj  

Dhcr24 activates the PI3K/Akt/HKII pathway and protects against dilated cardiomyopathy in mice [PDF]

, 2018
Wei Dong, Feifei Guan, Xu Zhang, Shan Gao, Ning Liu, Wei Chen, Lianfeng Zhang, Dan Lü   +7 more
openalex   +1 more source