Results 171 to 180 of about 69,694 (262)

Methylation-centric epigenetic regulation in dilated cardiomyopathy: mechanisms, metabolic interplay, and translational potential. [PDF]

Front Cardiovasc Med
Wang Y, Zhang Y, Mao Z, Xu Z.
europepmc   +1 more source

Mortality Trend in Patients With Heart Failure and Psychoactive Substance Abuse in the United States—Pre‐ and Post‐COVID‐19 Pandemic Perspective (1999−2023)

Clinical Cardiology, Volume 49, Issue 8, August 2026.
From 1999 to 2023, national HF‐substance abuse‐related mortality rates in adults rose over 10‐fold, disproportionately affecting males, older adults, and NH White and NH Black populations. Geographically, nonmetropolitan areas and the Midwestern/Northwestern regions saw the highest burden, signaling an urgent need for integrated cardiovascular and ...
Emad Uddin Sajid, Ayesha Irfan, Muhammad Kashan, Syed Rayyan Ahmed, Muhammad Hasnain Azeem, Tooba Ali, Mabel Waqar, Muneeba Khan, Erum Shahzadi Malik, Md Ariful Haque   +9 more
wiley   +1 more source

Primary dilated cardiomyopathy with LAMA2 and PKP4 mutations: imaging, genetics, and histology. [PDF]

Eur Heart J Case Rep
Zhou F, Li J, Lu M.
europepmc   +1 more source

Engineered exosomes improve myocardial cell membrane integrity and heart function in dystrophic cardiomyopathy

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
Schematic diagram of the manufacturing process of exosomes‐cardiac homing peptide (Exo‐CHP) and its therapeutic effects for Duchenne muscular dystrophy (DMD) cardiomyopathy. Abstract Background Duchenne muscular dystrophy (DMD)‐associated cardiomyopathy is a leading causes of premature death, yet treatment options remain limited.
Qihong Wu, Yiyuan Xue, Kun Zhang, Ke Xu, Ting Xu, Hang Fu, Suming Zhang, Meng Zhang, Ran Sun, Sophelia Hoi Shan Chan, Linyuhan Zhou, Xiaotang Cai, Yingkun Guo, Huayan Xu   +13 more
wiley   +1 more source

ADAMTS4 mediates LPS‐induced cardiac injury and myocardial fibrosis through proteolytic cleavage of TSP1

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
• ADAMTS4 is induced primarily in cardiac fibroblasts during sepsis. • ADAMTS4 cleaves TSP1 at the 236–246 aa functional region. • TSP1 cleavage activates TGF‐β/Smad and NF‐κB signalling in fibroblasts. • Targeting ADAMTS4 reduces fibroblast activation and cardiac fibrosis.
Zhe‐Wei Zhang, Shi‐Yan Wan, Wen Li, Xiao Lu, Rong Chen, Xin Xing, Wei Lai, Shu‐Yang Sheng, M. M. Mosebetsi, Qing‐Tao Meng, Zi‐Long Lu, Di Fan, Wan‐Li Jiang   +12 more
wiley   +1 more source

Comparing Outcomes of Heartmate 3 and Heart Transplantation in Older Children With Dilated Cardiomyopathy-Can Transplantation be Delayed or Avoided? [PDF]

Pediatr Transplant
Carlo WF, Padilla LA, Kirklin JK, Cantor RS, Koehl D, Jacobs JP, Amdani S, Chatfield K, Desai M, Vaughn G, Montgomery CM, Boucek K, Gambetta K, Morales DLS.   +13 more
europepmc   +1 more source

Frozen and Scorched: Genomic Signatures of Adaptive Divergence and Hibernation in the Living Fossil Dromiciops

Ecology and Evolution, Volume 16, Issue 8, August 2026.
We evaluated adaptation to torpor and hibernation in the genus Dromiciops by comparing it with both torpid and non‐torpid marsupials, and investigated divergent selection signals between its two species. For the ancestral node, we identified positive selection in the genes PFKFB2, LAMP3, OTX1, and RAPSN, alongside an enrichment of pathways potentially ...
Elisa Gonzalez‐Ugalde, Paula M. Avendaño, Julián F. Quintero‐Galvis, Eduardo J. Pizarro, Francisco A. Cubillos, Roberto F. Nespolo, Fabiola León, Juliana A. Vianna   +7 more
wiley   +1 more source

From gene to heart: the impact of a novel SGCD variant in familial dilated cardiomyopathy. [PDF]

BMC Med Genomics
Kalayinia S, Poopak A, Soveizi M, Maleki M.   +3 more
europepmc   +1 more source

Dose‐Dependent Anti‐Obesity and Protective Effects of Chia (Salvia hispanica L.) Seed Oil Against Hematological and Hepatorenal Dysfunction in High‐Fat Diet–Fed Mice

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Chia seed oil ameliorates obesity, dyslipidemia, and hepatorenal dysfunction in high‐fat diet–fed mice. ABSTRACT Chia seeds (Salvia hispanica L.) are recognized as a functional food with a nutrient‐dense profile and health‐promoting properties. In the present study, hexane‐extracted chia seed oil was investigated for anti‐obesity, hematoprotective, and
Sabbya Sachi, Mst. Prianka Jahan, Sree Alok Kumar, Mahmudul Hasan Sikder, Md. Zahorul Islam   +4 more
wiley   +1 more source

Diagnostic and Prognostic Utility of DNI and CRP in Patients with Dilated Cardiomyopathy. [PDF]

Int J Mol Sci
Söylemez N, Karaca Ö, Toprak B, Yılmaz S, Kılıç AT.   +4 more
europepmc   +1 more source