Results 181 to 190 of about 19,870 (257)
The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity
The Journal of Physiology, EarlyView.Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas +5 more
wiley +1 more source
Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes
The Journal of Physiology, EarlyView.Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière +6 more
wiley +1 more source
Circular RNAs: Unlocking new avenues in cardiometabolic disease management
The Journal of Physiology, EarlyView.Abstract figure legend In the heart circular RNAs (circRNAs) function as microRNA sponges, interact with proteins and can even undergo translation. Advances in bioinformatics now enable their identification through high‐throughput RNA sequencing, whereas computational analyses reveal differential expression in cardiac disease settings.
Kimberley M. Mellor +4 more
wiley +1 more source
Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights
The Journal of Physiology, EarlyView.Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò +18 more
wiley +1 more source
American Journal of Medical Genetics Part A, Volume 200, Issue 7, Page 1742-1748, July 2026.ABSTRACT The key diagnostic criterion for hypertrophic cardiomyopathy is the presence of otherwise unexplained hypertrophy. Current definitions of HCM rely on specific thresholds to establish a diagnosis, while guideline directed risk stratification algorithms take its magnitude into consideration.
Thomas D. Gossios +9 more
wiley +1 more source
Emerging Upper Extremity Muscle Ultrasound Patterns as a Diagnostic Aid in TTN‐Related Myopathies
Muscle &Nerve, Volume 74, Issue 1, Page 111-120, July 2026.ABSTRACT Introduction/Aims Biallelic pathogenic variants in TTN cause rare forms of early‐onset myopathy, manifesting with variable severity, distribution, and progression of muscle weakness, often associated with respiratory insufficiency and potentially cardiomyopathy. The large size of TTN and phenotypic heterogeneity in TTN‐related myopathy (TTN‐RM)
Abigail Potticary +3 more
wiley +1 more source
Sustainable Low‐Field Cardiovascular Magnetic Resonance in Changing Healthcare Systems—An Update
NMR in Biomedicine, Volume 39, Issue 7, July 2026.Low‐field cardiovascular MRI offers a cost‐effective and accessible alternative to conventional high‐field systems. Recent technological advances have improved image quality, safety, and device compatibility, expanding its clinical applications. These developments position low‐field CMR as a scalable solution to improve global cardiovascular imaging ...
Muhammad Umair +9 more
wiley +1 more source
Pre‐Sport Cardiac Evaluation in Children: Detection of Risks Other Than Sudden Cardiac Death
Annals of Noninvasive Electrocardiology, Volume 31, Issue 4, July 2026.In children who want to play sports, is a cardiac evaluation necessary only for sudden cardiac death? ABSTRACT Objective Sudden deaths may occur in children and adolescents due to unexpected cardiac problems during sports. This study aimed to screen for abnormalities that may lead to future morbidity in addition to the risk of sudden death and to ...
Mehmet Öncül, Abdulgani Gülyüz
wiley +1 more source
Causes of Persistent ST Elevation in Patients With Lung Cancer: A Case Report
Annals of Noninvasive Electrocardiology, Volume 31, Issue 4, July 2026.ST elevation without Q waves in advanced cancer may suggest cardiac metastasis; voltage gradient while repolarization may cause ST elevation in cardiac metastasis. ABSTRACT Cardiac metastases are rare in clinical practice. Herein, we describe the case of a 61‐year‐old male patient who underwent radical left lung cancer surgery > 2 years before the ...
Lijiang Ding, Huayong Jin
wiley +1 more source