Results 201 to 210 of about 117,472 (257)
Beyond Traditional Screening: The Future of Heart Failure Detection With Biomarkers and AI
Advancing HF Screening: Integrating Technology and Risk Factors Across Eras. This diagram provides a comprehensive review of the historical developments and projected trends of heart failure (HF) screening methodologies, with the prevalent risk factors for HF depicted at the base.
Xiaofeng Fang +9 more
wiley +1 more source
We report a 13‐year‐old female with a giant right ventricular myxoma extending to the pulmonary trunk. The tumor was diagnosed by multimodal imaging and completely resected, with favorable short‐term outcomes. ABSTRACT Right ventricular (RV) myxomas account for < 5% of cardiac myxomas and are often asymptomatic, easily overlooked.
Aizezi Maihemu +3 more
wiley +1 more source
ABSTRACT Pharmacological tools to selectively modulate extracellular vesicle (EV) secretion are scarce. Here, we identify the ALK5 (TGF‐β receptor I) inhibitor SD‐208 as a potent suppressor of small EV (sEV) secretion that acts independently of its canonical anti‐fibrotic activity.
Rahul Sanwlani +12 more
wiley +1 more source
Wetzel et al. outline how individual omics methods contribute to the diagnosis of patients with rare, and particularly mitochondrial diseases, with a focus on how spatial proteomics is joining this multi‐omics stack. ABSTRACT Proteomics by mass spectrometry has rapidly matured from a niche method into a standard tool.
Simon Wetzel +2 more
wiley +1 more source
From Common Pathway to Divergent Diseases: Metabolic Aspects of Inborn Errors of CoA Biosynthesis
ABSTRACT Coenzyme A (CoA) biosynthesis is a conserved, dynamically regulated pathway essential for mitochondrial energy production, fatty acid oxidation, lipid biosynthesis and protein acylation. Biallelic variants in PANK2, PPCS, PPCDC, and COASY cause rare inborn errors of CoA biosynthesis, associated with markedly different clinical phenotypes ...
Ivano Di Meo +3 more
wiley +1 more source
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Circulation Research, 2017
Dilated cardiomyopathy is defined by the presence of left ventricular dilatation and contractile dysfunction. Genetic mutations involving genes that encode cytoskeletal, sarcomere, and nuclear envelope proteins, among others, account for up to 35% of cases. Acquired causes include myocarditis and exposure to alcohol, drugs and toxins, and metabolic and
Elizabeth McNally
exaly +3 more sources
Dilated cardiomyopathy is defined by the presence of left ventricular dilatation and contractile dysfunction. Genetic mutations involving genes that encode cytoskeletal, sarcomere, and nuclear envelope proteins, among others, account for up to 35% of cases. Acquired causes include myocarditis and exposure to alcohol, drugs and toxins, and metabolic and
Elizabeth McNally
exaly +3 more sources
Current Opinion in Cardiology, 1994
The etiology and pathogenesis of dilated cardiomyopathy continues to be controversial. The importance of viral and familial etiologies is becoming increasingly recognized. Molecular biology will add significantly to our understanding of these factors in the near future.
S C, Siu, M J, Sole
openaire +2 more sources
The etiology and pathogenesis of dilated cardiomyopathy continues to be controversial. The importance of viral and familial etiologies is becoming increasingly recognized. Molecular biology will add significantly to our understanding of these factors in the near future.
S C, Siu, M J, Sole
openaire +2 more sources
The Lancet, 2010
Dilated cardiomyopathy is characterised by left ventricular dilation that is associated with systolic dysfunction. Diastolic dysfunction and impaired right ventricular function can develop. Affected individuals are at risk of left or right ventricular failure, or both. Heart failure symptoms can be exercise-induced or persistent at rest.
John Lynn, Jefferies, Jeffrey A, Towbin
openaire +2 more sources
Dilated cardiomyopathy is characterised by left ventricular dilation that is associated with systolic dysfunction. Diastolic dysfunction and impaired right ventricular function can develop. Affected individuals are at risk of left or right ventricular failure, or both. Heart failure symptoms can be exercise-induced or persistent at rest.
John Lynn, Jefferies, Jeffrey A, Towbin
openaire +2 more sources
Immunoadsorption in dilated cardiomyopathy
Transfusion and Apheresis Science, 2007Dilated cardiomyopathy (DCM) is a common myocardial disease characterized by ventricular dilatation and progressive depression of myocardial contractile function. Disturbances in both humoral and cellular immunity have been described among these patients. A number of antibodies against various cardiac cell proteins have been identified in DCM.
Alexander, Staudt, Stephan B, Felix
openaire +2 more sources
Alcoholic dilated cardiomyopathy
Nursing Standard, 2008This article provides an overview of alcoholic dilated cardiomyopathy. It aims to increase awareness of the condition among nurses, and help in early diagnosis and appropriate treatment referrals. The key message is that all patients with alcoholic dilated cardiomyopathy should be advised and assisted to stop drinking alcohol.
Anna, Adam +2 more
openaire +2 more sources

