Results 221 to 230 of about 19,870 (257)

Genetics of Dilated Cardiomyopathy

Heart Failure Clinics, 2010
Dilated cardiomyopathy (DCM) is a myocardial disorder defined by ventricular chamber enlargement and systolic dysfunction. DCM can result in progressive heart failure, arrhythmias, thromboembolism, and premature death, and contributes significantly to health care costs. In many cases, DCM results from acquired factors that affect cardiomyocyte function
Diane, Fatkin, Robyn, Otway, Zara, Richmond   +2 more
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Living with dilated cardiomyopathy

BMJ, 2016
Richard Mindham has been living with the diagnosed condition for nine years and shares his experiences as a ...
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Familial dilated cardiomyopathy

American Journal of Medical Genetics, 1988
AbstractIdiopathic dilated cardiomyopathy is generally considered a sporadic, nongenetic disorder, and reports of familial cases are often regarded as rare occurrences. Results of the present investigation of 6 families with this disorder suggest that familial forms of dilated cardiomyopathy occur more frequently than previously suspected. The familial
Michael A. Schmidt, Virginia V. Michels, William D. Edwards, Fletcher A. Miller, John M. Opitz, James F. Reynolds   +5 more
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Genetics of Dilated Cardiomyopathy

Current Cardiology Reports, 2018
Dilated cardiomyopathy (DCM) is characterized by left ventricular dilation and systolic function and is the most common among all cardiomyopathies. Familial DCM makes up a significant portion of cases, and approximately 40 genes are identified as involved in the pathogenesis of heart failure, each affecting a specific part of cellular mechanisms.
Yiwen, Fu, Howard J, Eisen
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Dilated cardiomyopathy: a review

Journal of Clinical Pathology, 2008
Dilated cardiomyopathy (DCM) is a common cardiac diagnosis that may result as a consequence of a variety of pathologies. The differential diagnosis remains quite broad since many pathologies can present as DCM, and as a result the approach to diagnosis may, at times, be quite difficult.
A, Luk, E, Ahn, G S, Soor, J, Butany
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Genetics in Dilated Cardiomyopathy

Biomarkers in Medicine, 2013
Discoveries made during the last 20 years have revealed a genetic origin in many cases of dilated cardiomyopathy (DCM). Currently, over 40 genes have been associated with the disease. Mutations in DCM-causing genes induce the condition through a variety of different pathological pathways with complex and not completely understood mechanisms. Genes that
Pablo, Garcia-Pavia, Marta, Cobo-Marcos, Gonzalo, Guzzo-Merello, Manuel, Gomez-Bueno, Belen, Bornstein, Enrique, Lara-Pezzi, Javier, Segovia, Luis, Alonso-Pulpon   +7 more
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Pharmacotherapy of Dilated Cardiomyopathy

Current Pharmaceutical Design, 2014
The pharmacological treatment of dilated cardiomyopathy overlaps with the treatment of heart failure. The primary objective of this treatment is to slow the progression of disease and improve quality and length of life. All patients, including those with asymptomatic dysfunction of the left ventricle, ought to receive angiotensin converting enzyme ...
Lenka, Spinarova, Jindrich, Spinar
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Immunoadsorption in Dilated Cardiomyopathy

2006
Dilated cardiomyopathy (DCM) is characterized by progressive reduction in contractile function and by dilatation of the right and left ventricles. Abnormalities of the cellular and humoral immune system are present in patients with myocarditis and DCM. Several antibodies against cardiac structures have been detected in DCM patients.
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Immunoadsorption in Dilated Cardiomyopathy

Therapeutic Apheresis, 2000
Abstract: The prognosis for patients suffering from advanced stages of dilated cardiomyopathy (DCM) is poor. Recent studies have shown that immunoadsorption (IA) may represent an effective alternative therapeutic approach for other kinds of autoimmune diseases with circulating autoantibodies. The objective of this pilot study was to ascertain the short‐
W V, Dörffel, G, Wallukat, G, Baumann, S B, Felix   +3 more
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Immunosuppression for Dilated Cardiomyopathy

New England Journal of Medicine, 1989
The diagnosis of dilated cardiomyopathy is made when left ventricular dilatation and systolic dysfunction, with normal wall thickness, occur in the absence of coronary artery, valvular, or pericardial disease.1 The right ventricle is also often involved.
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