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Dilated cardiomyopathy

European Heart Journal, 1984
On account of the rapidly progressive nature of the disease, the high incidence of systemic embolism and arrhythmias, and the risk of sudden death, dilated cardiomyopathy is inconsistent with aircrew duties. In the small proportion of subjects who apparently make a satisfactory recovery , re-licensing may be considered once there is no requirement for ...
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Anaphylatoxins in dilated cardiomyopathy

Journal of Internal Medicine, 1993
Abstract. Objects. The aim of the study was to investigate the possible relationship between activation of complement system and thromboembolic complications in dilated cardiomyopathy (DCMP).Methods. The plasma C3a and C5a concentrations were determined by radioimmunoassay measurement (Amersham International, UK) in 23 patients with DCMP, 9 with ...
M, Samsonov   +5 more
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Living with dilated cardiomyopathy

BMJ, 2016
Richard Mindham has been living with the diagnosed condition for nine years and shares his experiences as a ...
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Genetics of Dilated Cardiomyopathy

Heart Failure Clinics, 2010
Dilated cardiomyopathy (DCM) is a myocardial disorder defined by ventricular chamber enlargement and systolic dysfunction. DCM can result in progressive heart failure, arrhythmias, thromboembolism, and premature death, and contributes significantly to health care costs. In many cases, DCM results from acquired factors that affect cardiomyocyte function
Diane, Fatkin   +2 more
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Familial dilated cardiomyopathy

American Journal of Medical Genetics, 1988
AbstractIdiopathic dilated cardiomyopathy is generally considered a sporadic, nongenetic disorder, and reports of familial cases are often regarded as rare occurrences. Results of the present investigation of 6 families with this disorder suggest that familial forms of dilated cardiomyopathy occur more frequently than previously suspected. The familial
Michael A. Schmidt   +5 more
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Genetics of Dilated Cardiomyopathy

Current Cardiology Reports, 2018
Dilated cardiomyopathy (DCM) is characterized by left ventricular dilation and systolic function and is the most common among all cardiomyopathies. Familial DCM makes up a significant portion of cases, and approximately 40 genes are identified as involved in the pathogenesis of heart failure, each affecting a specific part of cellular mechanisms.
Yiwen, Fu, Howard J, Eisen
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Dilated cardiomyopathy: a review

Journal of Clinical Pathology, 2008
Dilated cardiomyopathy (DCM) is a common cardiac diagnosis that may result as a consequence of a variety of pathologies. The differential diagnosis remains quite broad since many pathologies can present as DCM, and as a result the approach to diagnosis may, at times, be quite difficult.
A, Luk, E, Ahn, G S, Soor, J, Butany
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Genetics in Dilated Cardiomyopathy

Biomarkers in Medicine, 2013
Discoveries made during the last 20 years have revealed a genetic origin in many cases of dilated cardiomyopathy (DCM). Currently, over 40 genes have been associated with the disease. Mutations in DCM-causing genes induce the condition through a variety of different pathological pathways with complex and not completely understood mechanisms. Genes that
Pablo, Garcia-Pavia   +7 more
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Inflammation in Dilated Cardiomyopathy

Herz, 2004
Inflammation is an important component in the pathogenesis of many common cardiovascular diseases. In most cases, the role of inflammation is a natural response to injury, and an important mechanism for healing and tissue repair. However, the inflammatory response can be either inadequate or overwhelming, leading to direct injury or severe host disease.
Sabine, Pankuweit   +2 more
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Immunoadsorption in Dilated Cardiomyopathy

2006
Dilated cardiomyopathy (DCM) is characterized by progressive reduction in contractile function and by dilatation of the right and left ventricles. Abnormalities of the cellular and humoral immune system are present in patients with myocarditis and DCM. Several antibodies against cardiac structures have been detected in DCM patients.
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