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Arrhythmias in Dilated Cardiomyopathy
Cardiac Electrophysiology Clinics, 2015Patients with dilated cardiomyopathies (DCM) face a significant burden of arrhythmias, including conduction defects such as atrioventricular block and interventricular delay in the form of left bundle branch block, resulting in altered electromechanical coupling that can exacerbate heart failure.
Saurabh, Kumar +2 more
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Dilated cardiomyopathy: an update
Veterinary Clinics of North America: Small Animal Practice, 2004Despite many advances in he diagnosis and treatment of DCM, it continues to be an important cause of cardiovascular morbidity and mortality in large-breed dogs. In the coming years, it is hoped and anticipated tht further discoveries will be made in the areas of etiology, therapy, and assessment of prognosis, ultimately with a view to having a greater ...
Michael R, O'Grady, M Lynne, O'Sullivan
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Pharmacotherapy of Dilated Cardiomyopathy
Current Pharmaceutical Design, 2014The pharmacological treatment of dilated cardiomyopathy overlaps with the treatment of heart failure. The primary objective of this treatment is to slow the progression of disease and improve quality and length of life. All patients, including those with asymptomatic dysfunction of the left ventricle, ought to receive angiotensin converting enzyme ...
Lenka, Spinarova, Jindrich, Spinar
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Immunoadsorption in Dilated Cardiomyopathy
Therapeutic Apheresis, 2000Abstract: The prognosis for patients suffering from advanced stages of dilated cardiomyopathy (DCM) is poor. Recent studies have shown that immunoadsorption (IA) may represent an effective alternative therapeutic approach for other kinds of autoimmune diseases with circulating autoantibodies. The objective of this pilot study was to ascertain the short‐
W V, Dörffel +3 more
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Immunoadsorption in Dilated Cardiomyopathy
2006Dilated cardiomyopathy (DCM) is characterized by progressive reduction in contractile function and by dilatation of the right and left ventricles. Abnormalities of the cellular and humoral immune system are present in patients with myocarditis and DCM. Several antibodies against cardiac structures have been detected in DCM patients.
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Immunopathogenesis of dilated cardiomyopathies
Current Opinion in Cardiology, 1995Idiopathic dilated cardiomyopathy is a chronic heart muscle disorder of unknown etiology, but experimental and clinical evidence is accumulating that points to an immune pathogenesis in a subset of patients, and to the potential importance of myosin as an antigen. Most recent developments include evidence of cardiac- and disease-specific autoantibodies
J H, Goldman, W J, McKenna
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Genetics of dilated cardiomyopathy
2000Dilated cardiomyopathy (DCM) is a heart muscle disorder characterized by cardiac dilatation and impaired systolic function. In an increasing number of all DCM cases a specific etiology can be identified and in the remaining patients DCM is termed idiopathic. There is a wide variation of the clinical presentation in DCM.
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Rare Variant Genetics and Dilated Cardiomyopathy Severity: The DCM Precision Medicine Study
Circulation, 2023Ray E Hershberger +2 more
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