Results 271 to 280 of about 592,769 (337)

Methylations in dilated cardiomyopathy and heart failure. [PDF]

Front Cardiovasc Med
Qin C, Qin Y, Zhou S.
europepmc   +1 more source

Truncating titin mutations are associated with a mild and treatable form of dilated cardiomyopathy

European Journal of Heart Failure, 2017
Joeri A Jansweijer, K. Nieuwhof, Francesco Russo, E. T. Hoorntje, J. Jongbloed, R. L. Lekanne Deprez, A. Postma, Marieke Bronk, Ingrid A van Rijsingen, S. de Haij, E. Biagini, P. L. van Haelst, J. V. van Wijngaarden, M. P. van den Berg, A. Wilde, M. Mannens, Rudolf A. de Boer, K. V. van Spaendonck-Zwarts, J. V. van Tintelen, Y. Pinto   +19 more
semanticscholar   +1 more source

FAM20A Deficiency Drives Transcriptomic Dysregulation and Functional Impairment in Gingival Fibroblasts

Cell Proliferation, EarlyView.
FAM20A variants cause AI1G, marked by enamel defects, gingival overgrowth and ectopic calcifications. RNA sequencing of patient‐derived gingival fibroblasts showed dysregulated genes in adhesion, proliferation and signalling pathways. Functional assays revealed increased cell proliferation, impaired ECM interactions and osteogenesis, suggesting FAM20A ...
Kanokwan Sriwattanapong, Sermporn Thaweesapphithak, Chompak Khamwachirapitak, Pannagorn Sae‐ear, Sasiprapa Prommanee, Noppadol Sa‐Ard‐Iam, Suphalak Phothichailert, Han Sung Jung, Vorasuk Shotelersuk, Thantrira Porntaveetus   +9 more
wiley   +1 more source

ATAD3 duplications bridge mitochondrial diseases and Aicardi–Goutières syndrome

Developmental Medicine &Child Neurology, EarlyView.
ATAD3 locus duplications cause a severe neonatal mitochondrial disorder with neuroimaging features resembling interferonopathies, and suggest a mitochondrial nucleic acid‐triggered interferon response. Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16446 Abstract A recurrent 68‐kb heterozygous duplication of the ATAD3 locus ...
Pauline Planté‐Bordeneuve, Claire‐Marine Bérat, Sylvain Hanein, Cyril Gitiaux, ATAD3 Study Group, Julie Steffann, Isabelle Desguerre, Agnès Rötig, Nathalie Boddaert, Giulia Barcia, Brian Sperelakis‐Beedham, Zahra Assouline, Marie‐Thérèse Abi‐Warde, Rukhshona Abdullazoda, Agnès Guichet, Céline Bris, Aurélien Caux, Marlène Rio, Jérémy Bertrand, Pauline Gaignard, Alice Lepelley, Arnold Munnich, Manuel Schiff, Isabelle Desguerre, Agnès Rötig, Nathalie Boddaert, Giulia Barcia   +26 more
wiley   +1 more source

Predictive value of ambulatory ECG monitoring for malignant arrhythmic events in genetic dilated cardiomyopathy. [PDF]

Europace
Venner MFGHM, Heymans ABM, Beelen NJ, Stroeks SLVM, Faassen IME, Sikking MA, Henkens MTHM, van der Crabben SN, Raafs AG, Heymans SRB, Verdonschot JAJ.   +10 more
europepmc   +1 more source

Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy

Science, 2015
J. T. Hinson, Anant Chopra, N. Nafissi, William Polacheck, Craig C. Benson, Sandra Swist, J. Gorham, Luhan Yang, S. Schafer, C. Sheng, A. Haghighi, Jason G. Homsy, N. Hubner, G. Church, S. Cook, W. Linke, Christopher S. Chen, J. Seidman, C. Seidman, C. Seidman, C. Seidman   +20 more
semanticscholar   +1 more source

Eplerenone improves kidney function and cardiac performance in obese male mice

Diabetic Medicine, EarlyView.
Abstract Aims Renin‐angiotensin‐aldosterone system (RAAS) activation mediates obesity‐associated cardiorenal dysfunction. Due to an incomplete understanding of the molecular mechanisms, the clinical use of RAAS antagonism in obesity‐associated cardiometabolic complications remains uncertain.
Ayman K. Banah, Bingxue Qi, Ryan Koh, Alexander Lawlor, Tianzhen Wang, Vishal Musale, Joanne Mains, Colin E. Murdoch, Li Kang   +8 more
wiley   +1 more source

Eosinophilic myocarditis in dilated cardiomyopathy: a case report. [PDF]

BMC Cardiovasc Disord
Li M, Chen H.
europepmc   +1 more source

TNNT2 Gene Polymorphisms are Associated with Susceptibility to Idiopathic Dilated Cardiomyopathy in Kazak and Han Chinese

, 2015
Yaodong Li, Yutong Ji, Xianhui Zhou, Hongliang Li, Hongtao Zhang, Qiang Xing, Yifan Hong, Baopeng Tang   +7 more
openalex   +2 more sources

Relevance of cardiac parvovirus B19 in myocarditis and dilated cardiomyopathy: review of the literature

European Journal of Heart Failure, 2016
J. Verdonschot, M. Hazebroek, J. Merken, Y. Debing, R. Dennert, H. Brunner-la Rocca, S. Heymans   +6 more
semanticscholar   +1 more source