Results 91 to 100 of about 1,208 (130)

β-Carboline-3-carboxamide Antimalarials: Structure-Activity Relationship, ADME-Tox Studies, and Resistance Profiling. [PDF]

open access: yesACS Infect Dis
Mathew J   +18 more
europepmc   +1 more source

Biowaiver monograph for immediate-release solid oral dosage forms: Amlodipine besylate. [PDF]

open access: yesJ Pharm Sci
de la Cruz-Cruz P   +13 more
europepmc   +1 more source

Formulation of Sustained-Release Verapamil HCl and Diltiazem HCl Semisolid Matrix Capsules

Pharmaceutical Development and Technology, 2008
Semisolid matrix capsule formulations of verapamil HCl and diltiazem HCl prepared by hot-melt capsule filling are an especially appealing and simple way to make sustained-release formulations. Semisolid matrices of Gelucire 50/13 and stearic acid combination eroded and disintegrated at various rates, depending on the combination of waxes, and drug ...
Chien Ngoc Nguyen   +2 more
exaly   +3 more sources

New colorimetric methods for the determination of trazodone HCl, famotidine, and diltiazem HCl in their pharmaceutical dosage forms

Analytical and Bioanalytical Chemistry, 2003
Two sensitive and simple spectrophotometric methods are developed for the determination of trazodone HCl, famotidine, and diltiazem HCl in pure and pharmaceutical preparations. The methods are based on the oxidation of the cited drugs with iron(III) in acidic medium.
Magda M Ayad   +2 more
exaly   +3 more sources

Pharmacokinetics of a Novel Diltiazem HCl Extended-Release Tablet Formulation for Evening Administration

Journal of Clinical Pharmacology, 2003
A novel diltiazem HCl extended‐release (ER) tablet formulation was developed for evening administration in the management of angina and hypertension. Pharmacokinetics of the formulation were evaluated to identify variations in morning (7 a.m. or 8 a.m.) versus evening (10 p.m.) drug administration.
Suryanarayana, Sista   +3 more
exaly   +3 more sources

Long-acting diltiazem HCL for the chronotherapeutic treatment of hypertension and chronic stable angina pectoris

Expert Opinion on Pharmacotherapy, 2005
Hypertension is associated with increased cardio- and cerebrovascular morbidity and mortality; antihypertensive drugs have been shown to reduce the risk of adverse cardio- and cerebrovascular events. These events tend to be more common during the morning hours, a time when both normo- and hypertensives show a circadian peak in blood pressure (BP ...
Steven A Claas, Stephen P Glasser
exaly   +3 more sources

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