Chronic pain remains the number one public health crisis in the US and around the world. Phenotypic screening assays for identifying novel analgesics are desperately needed. Here, the authors report on the development and characterization of an inflammatory nociception screening assay based on spontaneous and evoked activity from human induced ...
Bryan James Black +5 more
wiley +1 more source
We compare two of the most successful models for the description and analysis of drug release data. The fractal kinetics approach leading to release profiles described by a Weibull function and the fractional kinetics approach leading to release profiles
Kosmidis, Kosmas, Macheras, Panos
core +1 more source
Locust bean gum: exploring its potential for biopharmaceutical applications [PDF]
Polysaccharides have been finding, in the last decades, very interesting and useful applications in the biomedical and, specifically, in the biopharmaceutical field.
Dionísio, Marita, Grenha, Ana
core +2 more sources
Guru pembelajar modul paket keahlian farmasi SMK kelompok kompetensi H: teknik sediaan tablet, steril dan pelayanan farmasi, penilaian pembelajaran [PDF]
Modul Guru Pembelajar Mata Pelajaran Farmasi SMK ini terdiri atas 2 materi pokok, yaitu: materi profesional dan materi pedagogik. Masing-masing materi dilengkapi dengan tujuan, indikator pencapaian kompetensi, uraian materi, aktivitas pembelajaran ...
Hartati, Hartati, Nila, Aster
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In vitro evaluation of a morphine polymeric complex: flowability behavior and dissolution study [PDF]
The purpose of this research was to perform a granulometrical and flow properties study of a morphine polymeric complex and determine the influence of 3 variables—particle size of complex, pH value, and ionic strength of the dissolution medium—on the
Fernández Arévalo, María Mercedes +3 more
core +1 more source
What Drove First Year Premiums in Stand-Alone Medicare Drug Plans? [PDF]
Medicare's Part D offers heavily subsidized new drug coverage to 22.5 million seniors to date, of whom 16.5 million are in stand-alone drug plans (Department of Health and Human Services, 2006).
Claudio Lucarelli, Kosali I. Simon
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One of These Things Is Not Quite the Same: A Comparison of the Patent Doctrine of Equivalents with Suitability for Filing an Abbreviated New Drug Application [PDF]
The doctrine of equivalents as applied to chemical patents is compared to the FDA’s findings of bioequivalence in reviewing suitability petitions for filing Abbreviated New Drug Applications (ANDAs).
Halstead, David P.
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Drug release evaluation of Diltiazem HCl CR preparations [PDF]
Anurag Sood, Ramesh Panchagnula
openaire +1 more source
Application of 4-chloro-7-nitrobenzofurazan for the analysis of propafenone and diltiazem hydrochlorides using kinetic spectrophotometric and spectrofluorimetric methods [PDF]
Several simple, sensitive, accurate and inexpensive spectrophotometric and spectrofluorimetric methods were developed for the determination of propafenone HCl and diltiazem HCl using 4-chloro-7-nitrobenzofurazan (NBD-Cl) accompanied with kinetic study ...
Abdellatef, Hisham Ezzat +3 more
core +1 more source
Effects of an antimutagen of 1,4-dihydropyridine series on cell survival and DNA damage in L5178Y murine sublines [PDF]
In a series of studies it was shown that 1,4-dihydropyridine derivatives (1,4-DHP) show antimutagenic and anticlastogenic properties and accelerate repair of oxidant and ionising radiation generated DNA damage.
Dalivelya, Olga +1 more
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