Results 61 to 70 of about 4,480 (170)

Pleiotropic Effects of Calcium Channel Blockers [PDF]

open access: yes, 2012
Clinical trials have reported reduced cardiovascular events with certain antihypertensive agents at a rate that could not be predicted by changes in brachial arterial pressure alone.
Mason, R. Preston
core   +2 more sources

Impact of a Green Cabbage‐Based Diet on Selected Proinflammatory Cytokines and Hormones in Pre‐Eclamptic Rats

open access: yesJournal of Food Biochemistry, Volume 2025, Issue 1, 2025.
The growing interest in functional foods has led to the utilization of various vegetables for their nutritional benefits. This study focused on the development and evaluation of a green cabbage‐enriched meal and the investigation of the impact of the enriched cookies on selected proinflammatory cytokines and hormones in pre‐eclamptic Wistar rats.
Omolola Mary Omosebi   +3 more
wiley   +1 more source

Tools for clinical pharmacists to identify medications that can cause drug‐induced cognitive impairment: A systematic review

open access: yesJACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 7, Issue 12, Page 1207-1227, December 2024.
Abstract Cognitive impairment affects around 19% of community‐dwelling older adults in the United States. Pharmacists can play a significant role in identifying and deprescribing cognitive‐impairing medications through cognitive‐focused medication reviews or as part of comprehensive medication management.
Jacob Stanton   +4 more
wiley   +1 more source

Thinking Three‐Dimensionally: A Self‐ and Externally‐Controlled Approach to Screening for Drug–Drug–Drug Interactions Among High‐Risk Populations

open access: yesClinical Pharmacology &Therapeutics, Volume 116, Issue 2, Page 448-459, August 2024.
The global rise in polypharmacy has increased both the necessity and complexity of drug–drug interaction (DDI) assessments, given the growing potential for interactions involving more than two drugs. Leveraging large‐scale healthcare claims data, we piloted a semi‐automated, high‐throughput case‐crossover‐based approach for drug–drug–drug interaction ...
Emily K. Acton   +7 more
wiley   +1 more source

The Tissue‐Specific Eco‐Exposome: Differential Pharmaceutical Bioaccumulation and Disposition in Fish among Trophic Positions

open access: yesEnvironmental Toxicology and Chemistry, Volume 43, Issue 8, Page 1894-1902, August 2024.
Abstract Though bioaccumulation of pharmaceuticals by aquatic organisms continues to receive scientific attention, the internal disposition of these contaminants among different tissue compartments of fish species has been infrequently investigated, particularly among fish at different trophic positions. We tested a human to fish biological read‐across
Jaylen L. Sims   +8 more
wiley   +1 more source

Going Natural: Using polymers from nature for gastroresistant applications [PDF]

open access: yes, 2017
Nutraceuticals provide an additional health or medicinal benefit besides their nutritional value and are therefore marketed for the prevention and treatment of certain conditions.
Barbara Conway   +3 more
core   +1 more source

Pharmacokinetics and Pharmacodynamics of Etripamil, an Intranasally Administered, Fast‐Acting, Nondihydropyridine Calcium Channel Blocker

open access: yesClinical Pharmacology in Drug Development, Volume 13, Issue 4, Page 367-379, April 2024.
Abstract Etripamil, a fast‐acting nondihydropyridine L‐type calcium channel blocker, is under investigation for potential self‐administration for the acute treatment of supraventricular tachyarrhythmias in a medically unsupervised setting. We report detailed pharmacokinetics and pharmacodynamics of intranasally administered etripamil in healthy adults ...
James E. Ip   +5 more
wiley   +1 more source

An In-Depth Examination of Formularies and Other Features of Medicare Drug Plans [PDF]

open access: yes, 2006
Provides a detailed assessment of the formularies, drug costs, and utilization management tools offered by the fourteen nationwide organizations that account for most of the stand-alone prescription drug ...
Elizabeth Hargrave   +3 more
core  

Paradigm shift for preparing versatile M2+-free gels from unmodified sodium alginate [PDF]

open access: yes, 2017
This manuscript describes a new route to prepare rapidly Ca2+-free hydrogels from unmodified sodium alginate by simply mixing with small organic molecules such as poly(carboxylic acid) compounds as cross-linker agents instead of classical divalent metal ...
Alemán Llansó, Carlos   +5 more
core   +2 more sources

TRPV4 promotes HBV replication and capsid assembly via methylation modification of H3K4 and HBc ubiquitin

open access: yesJournal of Medical Virology, Volume 96, Issue 4, April 2024.
Abstract Hepatitis B virus (HBV) infection poses a significant burden on global public health. Unfortunately, current treatments cannot fully alleviate this burden as they have limited effect on the transcriptional activity of the tenacious covalently closed circular DNA (cccDNA) responsible for viral persistence.
Yu Zhang   +9 more
wiley   +1 more source

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