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Cardiovascular and Pharmacokinetic Profiles of Intravenous Etripamil in Conscious Telemetered Cynomolgus Monkeys. [PDF]
Int J ToxicolAscah A +4 more
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Development and Preclinical Evaluation of Fixed-Dose Capsules Containing Nicergoline, Piracetam, and Hawthorn Extract for Sensorineural Hearing Loss. [PDF]
PharmaceuticsRus LM +12 more
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Formulation of Sustained-Release Verapamil HCl and Diltiazem HCl Semisolid Matrix Capsules
Pharmaceutical Development and Technology, 2008Semisolid matrix capsule formulations of verapamil HCl and diltiazem HCl prepared by hot-melt capsule filling are an especially appealing and simple way to make sustained-release formulations. Semisolid matrices of Gelucire 50/13 and stearic acid combination eroded and disintegrated at various rates, depending on the combination of waxes, and drug ...
Chien N, Nguyen +2 more
exaly +3 more sources
Journal of Clinical Pharmacology, 2003
A novel diltiazem HCl extended‐release (ER) tablet formulation was developed for evening administration in the management of angina and hypertension. Pharmacokinetics of the formulation were evaluated to identify variations in morning (7 a.m. or 8 a.m.) versus evening (10 p.m.) drug administration.
Suryanarayana, Sista +3 more
exaly +3 more sources
A novel diltiazem HCl extended‐release (ER) tablet formulation was developed for evening administration in the management of angina and hypertension. Pharmacokinetics of the formulation were evaluated to identify variations in morning (7 a.m. or 8 a.m.) versus evening (10 p.m.) drug administration.
Suryanarayana, Sista +3 more
exaly +3 more sources
Analytical and Bioanalytical Chemistry, 2003
Two sensitive and simple spectrophotometric methods are developed for the determination of trazodone HCl, famotidine, and diltiazem HCl in pure and pharmaceutical preparations. The methods are based on the oxidation of the cited drugs with iron(III) in acidic medium.
Magda M Ayad
exaly +3 more sources
Two sensitive and simple spectrophotometric methods are developed for the determination of trazodone HCl, famotidine, and diltiazem HCl in pure and pharmaceutical preparations. The methods are based on the oxidation of the cited drugs with iron(III) in acidic medium.
Magda M Ayad
exaly +3 more sources
Effect of solvent type on retardation properties of diltiazem HCl form liquisolid tablets
Colloids and Surfaces B: Biointerfaces, 2014Liquisolid technique is a new approach to formulate sustained release dosage forms. It seems that the solubility of an active ingredient in solvent plays an important role in drug release profile. The aim of present study was to investigate the effect of solvent type on diltiazem hydrochloride release profile from liquisolid compacts.
Khosro Adibkia +2 more
exaly +3 more sources
Expert Opinion on Pharmacotherapy, 2005
Hypertension is associated with increased cardio- and cerebrovascular morbidity and mortality; antihypertensive drugs have been shown to reduce the risk of adverse cardio- and cerebrovascular events. These events tend to be more common during the morning hours, a time when both normo- and hypertensives show a circadian peak in blood pressure (BP ...
Steven A Claas, Stephen P Glasser
exaly +3 more sources
Hypertension is associated with increased cardio- and cerebrovascular morbidity and mortality; antihypertensive drugs have been shown to reduce the risk of adverse cardio- and cerebrovascular events. These events tend to be more common during the morning hours, a time when both normo- and hypertensives show a circadian peak in blood pressure (BP ...
Steven A Claas, Stephen P Glasser
exaly +3 more sources