Results 111 to 120 of about 1,208 (130)
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In vivo performance of controlled release pellets of diltiazem HCl.
Pakistan journal of pharmaceutical sciences, 2006The test formulation of controlled release diltiazem pellets was evaluated in vivo, in comparison with Herbesser SR. Six healthy volunteers participated in the study, conducted according to a randomized, two-way crossover study design. The preparations were compared using the pharmacokinetic parameters plasma concentration-time curve (AUC(0- infinity)),
, Nisarur-ur-Rahman +2 more
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Research Journal of Pharmacy and Technology, 2018
With emergence of new technology and concept, self-poring osmotic tablets were developed in order to reduce the complications and problems associated with micro drilling and laser drilling in osmotic tablet. This research describes a very simple and cheap method of developing self-poring osmotic tablet that deliver Diltiazem HCl in a controlled rate ...
Hemlata Thapa +17 more
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With emergence of new technology and concept, self-poring osmotic tablets were developed in order to reduce the complications and problems associated with micro drilling and laser drilling in osmotic tablet. This research describes a very simple and cheap method of developing self-poring osmotic tablet that deliver Diltiazem HCl in a controlled rate ...
Hemlata Thapa +17 more
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Formulation and Evaluation of Multi Particulate Extended-Release Dosage Form of Diltiazem HCl
International Journal of Drug Delivery TechnologyA multi-particulate extended-release dosage form of Diltiazem HCl was formulated and evaluated using drug layering technology to enhance dissolution and ensure controlled drug delivery. The study aimed to develop a stable and effective formulation with improved release characteristics.
R. Harish, Pavan Kumar Krosuri
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Clinical therapeutics, 1994
The safety and efficacy of an extended-release form of diltiazem HCl (diltiazem XR) in patients 55 years or older with mild-to-moderate essential hypertension were examined in a multi-center, double-blind, randomized, placebo-controlled, parallel-group study involving 350 patients with supine diastolic blood pressure (DBP) between 95 mm Hg and 114 mm ...
R, Fiddes +7 more
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The safety and efficacy of an extended-release form of diltiazem HCl (diltiazem XR) in patients 55 years or older with mild-to-moderate essential hypertension were examined in a multi-center, double-blind, randomized, placebo-controlled, parallel-group study involving 350 patients with supine diastolic blood pressure (DBP) between 95 mm Hg and 114 mm ...
R, Fiddes +7 more
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Pharmaceutical Development and Technology
Modified released formulations of diltiazem were previously prepared using cation-exchange resins. However, multiple excipients were required to achieve the appropriate release rate. It was of interest to prepare a modified release dosage form of diltiazem using drug-resin complex alone.Adsorption experiments conducted using a rotating bottle apparatus.
Khouloud A, Alkhamis, Suhair S, Al-Nimry
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Modified released formulations of diltiazem were previously prepared using cation-exchange resins. However, multiple excipients were required to achieve the appropriate release rate. It was of interest to prepare a modified release dosage form of diltiazem using drug-resin complex alone.Adsorption experiments conducted using a rotating bottle apparatus.
Khouloud A, Alkhamis, Suhair S, Al-Nimry
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1993
The primary means of administration for the vast majority of therapeutic agents is via the oral route. Many of these oral dosage forms are designed to provide a rapid disintegration in the stomach, however, over the last 5–6 years there has been a growing trend within the pharmaceutical industry to develop complex pharmaceutical dosage forms designed ...
Donald L. Heald +2 more
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The primary means of administration for the vast majority of therapeutic agents is via the oral route. Many of these oral dosage forms are designed to provide a rapid disintegration in the stomach, however, over the last 5–6 years there has been a growing trend within the pharmaceutical industry to develop complex pharmaceutical dosage forms designed ...
Donald L. Heald +2 more
openaire +1 more source