Results 101 to 110 of about 2,144,368 (379)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Mixing and dilution controls on marine CO2 removal using alkalinity enhancement

Environmental Research Letters
Marine CO _2 removal (CDR) using enhanced-alkalinity seawater discharge was simulated in the estuarine waters of the Salish Sea, Washington, US. The high-alkalinity seawater would be generated using bipolar membrane electrodialysis technology to remove ...
Tarang Khangaonkar, Brendan R Carter, Lakshitha Premathilake, Su Kyong Yun, Wenfei Ni, Mary Margaret Stoll, Nicholas D Ward, Lenaïg G Hemery, Carolina Torres Sanchez, Chinmayee V Subban, Mallory C Ringham, Matthew D Eisaman, Todd Pelman, Krti Tallam, Richard A Feely   +14 more
doaj   +1 more source

Surface Energy Mapping of Modified Silica Using IGC Technique at Finite Dilution [PDF]

, 2020
Yen Wan Ngeow, Daryl R. Williams, Andrew V. Chapman, Jerry Y. Y. Heng   +3 more
openalex   +1 more source

Phase boundary detection for dilution refrigerators

, 2004
We describe a device to conveniently measure the positions of the phase boundaries in a dilution refrigerator. We show how a simple modification of a standard capacitive level gauge (segmentation of one of the electrodes) permits a direct calibration of ...
Martin, R. V., ter Haar, E.
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Efeito da restrição alimentar qualitativa no desempenho, na incidência de distúrbios metabólicos e no rendimento de carcaça em frangos de corte Qualitative feed restriction effects on growth performance, metabolic disorders and carcass traits of broiler chickens

Revista Brasileira de Zootecnia, 1999
Este estudo foi realizado para avaliar o desempenho, o controle da manifestação de doenças metabólicas e o rendimento de carcaça de frangos de corte machos submetidos à restrição alimentar no período de 8 a 14 dias de idade.
Helenice Mazzuco, Fátima Regina Jaenisch, Antonio Lourenço Guidoni   +2 more
doaj   +1 more source

Simplified Modelling of Inclined Turbulent Dense Jets

Fluids, 2020
An analytical approximation to the entire centerline trajectory of inclined round dense jets in dimensionless form is proposed, in terms of a fourth degree polynomial.
Ilias G. Papakonstantis, George C. Christodoulou   +1 more
doaj   +1 more source

Implementing Microwave Impedance Microscopy in a Dilution Refrigerator [PDF]

, 2023
Zhanzhi Jiang, Su Kong Chong, Peng Zhang, Deng Peng, Shizai Chu, Shahin Jahanbani, Kang Lung Wang, Keji Lai   +7 more
openalex   +1 more source

Dilution Zone Mixing [PDF]

, 1983
Studies to characterize dilution zone mixing; experiments on the effects of free-stream turbulence on a jet in crossflow; and the development of an interactive computer code for the analysis of the mixing of jets with a confined crossflow are ...
Holdeman, J. D.
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source